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Exon ligation is proofread by the DExD/H-box ATPase Prp22p
- Rabiah M Mayas, H. Maita, J. P. Staley
- Biology, Medicine
- Nature Structural &Molecular Biology
- 7 May 2006
To produce messenger RNA, the spliceosome excises introns from precursor (pre)-mRNA and splices the flanking exons. To establish fidelity, the spliceosome discriminates against aberrant introns, but… Expand