Raanan Cohen-Kerem

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Ethanol is the most common human teratogen, and heavy drinking during pregnancy can result in serious adverse outcomes to the fetus. The cellular mechanisms by which ethanol induces damage in utero are not well understood, while induction of oxidative stress is believed to be one putative mechanism. Our objective is to review the data of antioxidant effects(More)
OBJECTIVES To systematically review the published experience on intratympanic gentamicin treatment for intractable Menière's disease. STUDY DESIGN Meta-analysis using a random effect model. METHODS A comprehensive literature search was performed for articles using intratympanic gentamicin as a sole treatment modality with reporting of results according(More)
OBJECTIVE To evaluate the effects of non-obstetric surgical procedures on maternal and fetal outcome. METHODS A systematic review of all English language literature. RESULTS Fifty-four papers met the inclusion criteria. The overall number of patients reported was 12,452. Reported maternal death was rare at .006%. The miscarriage rate was 5.8%; however,(More)
BACKGROUND Azathioprine (AZP) interferes with nucleic acid synthesis and is teratogenic in animals. In view of the paucity of information on the use of AZP during pregnancy we investigated this subject in a prospective, controlled, multicenter study. Our objective was too determine whether exposure to AZP during pregnancy increases the risk for major(More)
OBJECTIVE To characterize inherent acoustic abnormalities of the deaf pediatric voice and the effect of artificially restoring auditory feedback with cochlear implantation. DESIGN Inception cohort. SETTING Academic referral center. PATIENTS Twenty-one children with severe to profound hearing loss (15 prelingually deaf, 6 postlingually deaf) accepted(More)
OBJECTIVES To characterize aneurysmal bone cysts (ABCs) of the head and neck as seen at a tertiary care center. DESIGN A case series. METHODS A retrospective chart review of pediatric patients with aneurysmal bone cyst of the head and neck treated at the Hospital for Sick Children during the years 1994-2006 was carried out. RESULTS Nine patients with(More)
The association between asthma and sinonasal disease has been known for years. Effective treatment of sinonasal disease, which is one of the factors that exacerbate asthma, may also improve and stabilize the asthmatic condition. This study examines the outcome of functional endoscopic sinus surgery (FESS) on asthmatic patients with massive nasal polyposis.(More)
To assess cytokeratin-17 (CK17) as an immunohistochemical marker for squamous cell carcinoma of the larynx, we stained 63 tissue samples from 63 consecutive patients who were believed or suspected to have squamous cell carcinoma of the larynx for CK17 and analyzed them by computerized histomorphometry. The mean staining intensity for CK17 was significantly(More)
Surgical management of multinodular goiter (MNG) poses an ongoing dilemma between radical resection with its associated complications and partial resection, which carries the risk of recurrence and increased morbidity and difficulty for rethyroidectomy. This study was designed to evaluate the recurrence rate and need for reoperation in a carefully selected(More)