Raúl Bonne Hernández

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Manganese (Mn) is an essential trace element required for the proper functioning of a variety of physiological processes. However, chronic exposures to Mn can cause neurotoxicity in humans, especially when it occurs during critical stages of the central nervous system development. The mechanisms mediating this phenomenon as well as the contribution of Mn(More)
Manganese (Mn) is an essential nutrient that can be toxic in excess concentrations, especially during early development stages. The mechanisms of Mn toxicity is still unclear, and little information is available regarding the role of Mn speciation and fractionation in toxicology. We aimed to investigate the toxic effects of several chemical forms of Mn in(More)
O presente estudo forneceu dados para o cálculo das constantes de estabilidade formadas em um sistema aquoso e HCl contendo quitosana e cátions Cu2+, Mn2+ e Zn2+. Os diagramas de espécies foram gerados para demonstrar como o pH influencia esses equilíbrios estudados por titulações potenciométricas e espectrofotométricas. Os sólidos extraídos dessas soluções(More)
Manganese (Mn) is an essential trace element and trivalent Mn complexes have been used as oxidation catalysts and enzyme mimetics. We studied the cytotoxicity of Mn(III) derivatives of citrate, pyrophosphate and salicylene diamine (respectively, MnCit, MnPPi and EUK8) toward HeLa cells stressed by ultraviolet irradiation and the effect of the(More)
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