Raúl A Vignale

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The number of scratching episodes and average frequency with which they started during each sleep stage as well as the effects of nighttime pruritus on objective sleep parameters in nine children with atopic dermatitis were assessed in the sleep laboratory. Scratching episodes occurred during rapid eye movement (REM) sleep and non-REM (NREM) sleep. The(More)
Vitiligo is a disease of melanocytes characterized by achromic lesions in the skin, affecting the epidermis and the pilosebaceous follicle. We performed an ultrastructural analysis of biopsy specimens from four patients with noninflammatory, stable vitiligo of long duration (three had generalized vitiligo and one had segmental vitiligo). The samples were(More)
BACKGROUND To date the direct fresh examination has not been considered, except by a few authors, as a valid laboratory procedure for the diagnosis of cutaneous sporotrichosis. METHODS Forty-two patients with cutaneous sporotrichosis (36 lymphangitic and six fixed) were studied. Pus was obtained through digital compression of opened lesions followed by(More)
Four members of a family with consanguineous relationships, the proband and his three children (2 sons and 1 daughter) are affected with Familial Spastic Ataxia and with Ehlers-Danlos' Syndrome with platelet aggregation dysfunction. In the four cases, this exceptional association appears remarkably homogeneous both in clinical and laboratory studies. The(More)
Few studies have been made about the influence of the autonomous nervous system on the proliferation of malignant cells. The aim of this work was to investigate if there is any relationship between the aggressiveness of basal cell carcinoma (BCC) and the presence of nerve fibres. We studied 20 samples of BCC, classified in two groups: non aggressive and(More)
Antireticulin antibodies were studied in the sera of 32 patients affected by various clinical forms of psoriasis. The indirect immunofluorescence method was used on histological sections of human kidney and mouse liver and kidney. This method was also used with sera from children with coeliac disease and from healthy controls. In 10 these antibodies were(More)