RP Woitas

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To the Editor: Inulin clearance (C In) is the usual gold standard for evaluating glomer-ular filtration rate (GFR), but technical difficulties and patient inconvenience prevent its widespread use (1). The most commonly used marker for GFR is serum creatinine, but muscle wasting and tubular secretion may lead to overestimation of GFR (2, 3). Serum(More)
BACKGROUND Plasma creatinine and creatinine clearance are of limited value for the estimation of renal function in cirrhotics. In these patients, cystatin C (Cys C) has been proposed as an alternative marker of glomerular filtration rate (GFR) and Cys C-based equations for calculation of GFR have been developed in non-cirrhotic patient cohorts. METHODS We(More)
OBJECTIVES Chronic kidney disease is frequent in patients after orthotopic liver transplantation (OLT) and has impact on survival. Patients receiving calcineurin inhibitors (CNI) are at increased risk to develop impaired renal function. Early CNI reduction and concomitant use of mycophenolat mofetil (MMF) has been shown to improve renal function. METHODS(More)
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