RJ Daly

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In vertebrates, Grb2-associated binder (Gab)1–3 constitute a family of conserved docking proteins. Gab2 is tyro-sine-phosphorylated upon activation of a variety of growth factor, hormone, antigen, cytokine and cell matrix receptors, leading to the recruitment of specific src homol-ogy (SH)2 domain-containing effectors, which include the p85 subunit of(More)
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