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Outpatient psychotherapy for borderline personality disorder: randomized trial of schema-focused therapy vs transference-focused psychotherapy.
Three years of SFT or TFP proved to be effective in reducing borderline personality disorder-specific and general psychopathologic dysfunction and in improving quality of life; SFT is more effective than TFP for all measures.
Anxiety disorders in later life: a report from the longitudinal aging study Amsterdam
The prevalence and risk factors of anxiety disorders in the older (55–85) population of The Netherlands are studied to find out if older people are more likely to suffer from anxiety disorders.
The Netherlands Study of Depression and Anxiety (NESDA): rationale, objectives and methods
The Netherlands Study of Depression and Anxiety (NESDA) is a multi‐site naturalistic cohort study to: (1) describe the long‐term course and consequences of depressive and anxiety disorders, and (2)
The Development and Psychometric Characteristics of the Somatoform Dissociation Questionnaire (SDQ‐20)
The Somatoform Dissociation Questionnaire (SDQ-20) is a scale of good psychometric quality, which measures somatoform dissociation, and the symptoms pertain to negative and positive dissociative phenomena, which were well known in 19th century French psychiatry as the mental stigmata and mental accidents of hysteria.
Anxiety and depression in later life: Co-occurrence and communality of risk factors.
Although high levels of comorbidity between major depressive Disorder and anxiety disorders were found, comparing risk factors associated with pure major depressive disorder and pure anxiety disorders revealed more differences than similarities.
Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study.
This large cohort study shows significant, although modest, associations between major depressive disorder and specific hypothalamic-pituitary-adrenal axis indicators and a higher cortisol awakening response was observed among both subjects with current MDD and subjects with remitted MDD, indicative of an increased biological vulnerability for depression.
Association between major depressive disorder and heart rate variability in the Netherlands Study of Depression and Anxiety (NESDA).
This study shows that depression is associated with significantly lowered heart rate variability, however, this association appears to be mainly driven by the effect of antidepressants.
Genomewide Association for Major Depressive Disorder: A possible role for the presynaptic protein Piccolo
A genome-wide association study of single nucleotide polymorphisms genotyped in 1738 MDD cases and 1802 controls selected to be at low liability for MDD found 11 signals localized to a 167 kb region overlapping the gene piccolo, whose protein product localizes to the cytomatrix of the presynaptic active zone and is important in monoaminergic neurotransmission in the brain.