• Publications
  • Influence
Acute regulation of tyrosine hydroxylase by nerve activity and by neurotransmitters via phosphorylation.
Although stimulation of adrenergic nerves or adrenal chromaffin cells causes the release of catecholamines, in many cases it does not cause a decrease in the catecholamine content of these cells. OneExpand
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Localization of neurons in the rat spinal cord which project to the superior cervical ganglion
Horseradish peroxidase (HRP) was used to determine the location in the spinal cord of neurons projecting to the superior cervical ganglion of the rat. HRP was applied to the proximal cut end of theExpand
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Characterization of a snake venom neurotoxin which blocks nicotinic transmission in the avian ciliary ganglion
Bungarus multicinctus venom was fractionated by ion exchange chromatography and the various fractions were assayed for their ability to block synaptic transmission through the chick ciliary ganglion.Expand
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Nerve Growth Factor Antiserum Induces Axotomy-Like Changes in Neuropeptide Expression in Intact Sympathetic and Sensory Neurons
Axonal transection of adult sympathetic and sensory neurons leads to a decrease in their content of target-derived nerve growth factor (NGF) and to dramatic changes in the expression of severalExpand
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Novel changes in gene expression following axotomy of a sympathetic ganglion: a microarray analysis.
Neurons of the peripheral nervous system are capable of extensive regeneration following axonal injury. This regenerative response is accompanied by changes in gene expression in axotomized neuronsExpand
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The neuroimmunology of degeneration and regeneration in the peripheral nervous system
Peripheral nerves regenerate following injury due to the effective activation of the intrinsic growth capacity of the neurons and the formation of a permissive pathway for outgrowth due to WallerianExpand
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gp130 cytokines are positive signals triggering changes in gene expression and axon outgrowth in peripheral neurons following injury
  • R. Zigmond
  • Biology, Medicine
  • Front. Mol. Neurosci.
  • 20 January 2012
Adult peripheral neurons, in contrast to adult central neurons, are capable of regeneration after axonal damage. Much attention has focused on the changes that accompany this regeneration in twoExpand
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Regulation of vasoactive intestinal peptide expression in sympathetic neurons in culture and after axotomy: the role of cholinergic differentiation factor/leukemia inhibitory factor.
Vasoactive intestinal peptide (VIP) expression increases in sympathetic neurons when they are grown in dissociated cell or explant cultures and when they are axotomized in vivo. In dissociated cellExpand
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Galanin expression increases in adult rat sympathetic neurons after axotomy
Changes in neuropeptide expression occur in sensory, motor, and sympathetic neurons following axotomy. The particular pattern of peptide changes that occurs varies among the three cell types. We haveExpand
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Vasoactive Intestinal Peptide Stimulates Catecholamine Biosynthesis in Isolated Adrenal Chromaffin Cells: Evidence for a Cyclic AMP‐Dependent Phosphorylation and Activation of Tyrosine Hydroxylase
Vasoactive intestinal peptide (VIP) increased catecholamine biosynthesis in bovine adrenal chromaffin cells by 50–200%. Six related peptides produced no effects. In addition, VIP increased tyrosineExpand
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