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Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress
TLDR
It is proposed that oxidative stress and the ensuing cellular adaptations are linked to the schizophrenia disease process and it is hoped that this new disease concept may advance the approach to treatment, diagnosis and disease prevention of schizophrenia and related syndromes.
Antibodies to Toxoplasma gondii in patients with schizophrenia: a meta-analysis.
TLDR
The results suggest that individuals with schizophrenia have an increased prevalence of antibodies to T. gondii, and this association is consistent with other epidemiological studies as well as with animal studies.
DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.
TLDR
It is shown that a specific interaction between DISC1 and nuclear distribution element-like (NDEL1/NUDEL) is required for neurite outgrowth in differentiating PC12 cells.
Toxoplasma gondii and Schizophrenia
TLDR
Establishing the role of T. gondii in the etiopathogenesis of schizophrenia might lead to new medications for its prevention and treatment.
Maternal Cytokine Levels during Pregnancy and Adult Psychosis
TLDR
Levels of maternal cytokines in late pregnancy in relation to the subsequent development of adult schizophrenia and other psychoses in their offspring support previous clinical investigations reporting maternal infections during pregnancy as a potential risk factor for psychotic illness among offspring.
Beyond the association. Toxoplasma gondii in schizophrenia, bipolar disorder, and addiction: systematic review and meta‐analysis
TLDR
A meta‐analysis on studies reporting prevalence of Toxoplasma gondii infection in any psychiatric disorder compared with healthy controls to analyze factors possibly moderating heterogeneity.
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