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Chlorthalidone Decreases Platelet Aggregation and Vascular Permeability and Promotes Angiogenesis
Variations in diuretic-mediated inhibition of carbonic anhydrase-dependent chloride transport in platelets and vascular smooth muscle could account for the contrasting efficacy of the thiazide andExpand
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Preserving cardiac output with beta-adrenergic receptor blockade and inhibiting the Bezold-Jarisch reflex during resuscitation from hemorrhage.
BACKGROUND Successful fluid resuscitation after severe hemorrhage may be limited by activation of the Bezold-Jarisch reflex. We postulated that pharmacologic inhibition of this reflex would restoreExpand
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Ephedra alkaloids inhibit platelet aggregation
Sympathomimetics, such as Ephedra alkaloids, are associated with an increased incidence of intracerebral hemorrhage believed to be secondary to concomitant elevations in blood pressure. WeExpand
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Alpha-methyltyrosine inhibits formation of reactive oxygen species and diminishes apoptosis in PC12 cells
OBJECTIVE Circulating catecholamines and adrenal steroids are significantly increased following traumatic brain injury, and elevations in plasma catecholamines and cortisol portend a poor outcome. WeExpand
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Cyclic Adenosine Monophosphate Accumulation and {5-Adrenergic Binding in Unweighted and Denervated Rat Soleus Muscle
Unweighting, but not denervation, of muscle reportedly "spares" insulin receptors, increasing insulin sensitivity. Unweighting also increases I_-adrenergic responses of carbohydrate metabolism. TheseExpand