Dopamine, learning and motivation
- R. Wise
- Psychology, BiologyNature Reviews Neuroscience
- 1 June 2004
Dopamine release in the nucleus accumbens has been linked to the efficacy of these unconditioned rewards, but dopamine release in a broader range of structures is implicated in the 'stamping-in' of memory that attaches motivational importance to otherwise neutral environmental stimuli.
A psychomotor stimulant theory of addiction.
- R. Wise, M. Bozarth
- Psychology, BiologyPsychology Review
- 1 October 1987
A new attempt at a general theory of addiction is offered, based on the common denominator of the psychomotor stimulants---amphetamine, cocaine, and related drugs---rather than on thecommon denominators of the socalled depressant drugs~opiates, barbiturates, alcohol, and others.
Intermittent access to 20% ethanol induces high ethanol consumption in Long-Evans and Wistar rats.
- J. Simms, P. Steensland, S. Bartlett
- MedicineAlcoholism: Clinical and Experimental Research
- 1 October 2008
The cycles of excessive drinking and abstinence led to an increase in ethanol preference and increased efficacy of both acamprosate and naltrexone in Long-Evans rats, which promises to be a valuable tool in the alcohol research field.
Synaptic and Behavioral Profile of Multiple Glutamatergic Inputs to the Nucleus Accumbens
- J. P. Britt, F. Benaliouad, R. McDevitt, G. Stuber, R. Wise, A. Bonci
- Biology, PsychologyNeuron
- 21 November 2012
Dopamine Uptake through the Norepinephrine Transporter in Brain Regions with Low Levels of the Dopamine Transporter: Evidence from Knock-Out Mouse Lines
- J. Morón, A. Brockington, R. Wise, B. Rocha, B. Hope
- Biology, PsychologyJournal of Neuroscience
- 15 January 2002
Comparing the effects of inhibitors selective for the three monoamine transporters with those of a nonspecific inhibitor, cocaine, on uptake of 3H-dopamine into synaptosomes from frontal cortex, caudate nucleus, and nucleus accumbens from wild-type, NET, and dopamine transporter (DAT) knock-out mice suggests that dopamine in this region is normally cleared by the somewhat promiscuous NET.
Neuroadaptation: Incubation of cocaine craving after withdrawal
- Jeffrey W Grimm, B. Hope, R. Wise, Y. Shaham
- Psychology, BiologyNature
- 12 July 2001
Behavioural evidence is provided from laboratory animals suggesting that the onset of craving is delayed and that craving does not decay, but rather increases progressively, over a two-month withdrawal period.
Cocaine Experience Establishes Control of Midbrain Glutamate and Dopamine by Corticotropin-Releasing Factor: A Role in Stress-Induced Relapse to Drug Seeking
- Bin Wang, Y. Shaham, D. Zitzman, Soraya Azari, R. Wise, Z. You
- Biology, PsychologyJournal of Neuroscience
- 1 June 2005
A long-lasting cocaine-induced neuroadaptation, presumably at the level of glutamate terminals in the VTA, appears to play an important role in stress-induced relapse to drug use.
Addictive drugs and brain stimulation reward.
- R. Wise
- Biology, PsychologyAnnual Review of Neuroscience
- 1996
The reward-potentiating effects of amphetamine and opiates are associated with central sites of action where these drugs also have their direct rewarding effects, suggesting common mechanisms for drug reward per se and for drug potentiation of brain stimulation reward.
Brain Reward Circuitry Insights from Unsensed Incentives
- R. Wise
- Psychology, BiologyNeuron
- 10 October 2002
Brain dopamine and reward.
While the evidence is strong that dopamine plays some fundamental and special role in the rewarding effects of brain stimulation, psychomotor stimulants, opiates, and food, the exact nature of that…
...
...