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Resting fluctuations in arterial carbon dioxide induce significant low frequency variations in BOLD signal
We have identified a significant source of low-frequency variation in blood oxygen level-dependent (BOLD) magnetic resonance imaging (MRI) signal arising from spontaneous fluctuations in arterial carbon dioxide level in volunteers at rest. Expand
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Imaging how attention modulates pain in humans using functional MRI.
Current clinical and experimental literature strongly supports the phenomenon of reduced pain perception whilst attention is distracted away from noxious stimuli. This study used functional MRI toExpand
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Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. HereExpand
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Quantitative fMRI assessment of the differences in lateralization of language-related brain activation in patients with temporal lobe epilepsy
We have used fMRI to study healthy controls and patients with TLE in order to (i) define language-related activation patterns and their reproducibility; (ii) compare lateralization determined by fMRI with those from the Wada test; and (iii) contrast different methods of assessing fMRI lateralization. Expand
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Neural correlates of the LSD experience revealed by multimodal neuroimaging
Significance Lysergic acid diethylamide (LSD), the prototypical “psychedelic,” may be unique among psychoactive substances. In the decades that followed its discovery, the magnitude of its effect onExpand
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Physiological noise modelling for spinal functional magnetic resonance imaging studies
Spinal cord functional imaging allows assessment of activity in primary synaptic connections made by sensory neurons relaying information about the state of the body. Expand
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Cerebral Perfusion Response to Hyperoxia
Graded levels of supplemental inspired oxygen were investigated for their viability as a noninvasive method of obtaining intravascular magnetic resonance image contrast. Administered hyperoxia hasExpand
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Measurement of OEF and absolute CMRO2: MRI-based methods using interleaved and combined hypercapnia and hyperoxia
We show that combined modulation of oxygen and carbon dioxide can offer an experimentally more efficient approach to estimating absolute CMRO2 along with the additional vascular parameters that form an important part of the commonly used calibrated fMRI signal model. Expand
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A multisensory investigation of the functional significance of the “pain matrix”
Functional neuroimaging studies in humans have shown that nociceptive stimuli elicit activity in a wide network of cortical areas commonly labeled as the "pain matrix" and thought to be preferentially involved in the perception of pain. Expand
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Brainstem functional magnetic resonance imaging: Disentangling signal from physiological noise
To estimate the importance of respiratory and cardiac effects on signal variability found in functional magnetic resonance imaging data recorded from the brainstem.
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