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Predictive value of seven preoperative prognostic scoring systems for spinal metastases
Predicting prognosis is the key factor in selecting the proper treatment modality for patients with spinal metastases. Therefore, various assessment systems have been designed in order to provide a… Expand
Failure mode classification for tumor endoprostheses: retrospective review of five institutions and a literature review.
- E. Henderson, John S Groundland, +11 authors G. Letson
- The Journal of bone and joint surgery. American…
- 2 March 2011
BACKGROUND Massive endoprostheses provide orthopaedic oncologists with many reconstructive options after tumor resection, although failure rates are high. Because the number of these procedures is… Expand
Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation
BackgroundHuman mesenchymal stem cells (MSC) with the capacity to differentiate into osteoblasts provide potential for the development of novel treatment strategies, such as improved healing of large… Expand
Aneurysmal bone cyst. A population based epidemiologic study and literature review.
- A. Leithner, R. Windhager, S. Lang, O. Haas, F. Kainberger, R. Kotz
- Clinical orthopaedics and related research
- 1 June 1999
Aneurysmal bone cyst is a rare nonneoplastic expansile osteolytic bone lesion of unknown etiology. To the best of the authors' knowledge, no epidemiologic study concerning its incidence has been… Expand
Increasing incidence rates of soft tissue sarcomas? A population-based epidemiologic study and literature review.
- C. Wibmer, A. Leithner, N. Zielonke, M. Sperl, R. Windhager
- Annals of oncology : official journal of the…
- 1 May 2010
BACKGROUND Increasing incidence rates of soft tissue sarcomas (STS) have been reported. In the present study, the authors have analyzed the incidence of STS in Austria in a population-based study for… Expand
Quality of life and psychosocial adjustment of young patients after treatment of bone cancer
The aim of this study was to collect information about the psychosocial situation of young patients after multimodality therapy for bone cancer.
Articular cartilage repair by genetically modified bone marrow aspirate in sheep
Bone marrow presents an attractive option for the treatment of articular cartilage defects as it is readily accessible, it contains mesenchymal progenitor cells that can undergo chondrogenic… Expand
Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to…
- S. Bielack, S. Smeland, +46 authors M. Bernstein
- Journal of clinical oncology : official journal…
- 1 June 2015
Purpose EURAMOS-1, an international randomized controlled trial, investigated maintenance therapy with pegylated interferon alfa-2b (IFN-α-2b) in patients whose osteosarcoma showed good histologic… Expand
Undifferentiated human mesenchymal stem cells (hMSCs) are highly sensitive to mechanical strain: transcriptionally controlled early osteo-chondrogenic response in vitro.
- G. Friedl, H. Schmidt, I. Rehák, G. Kostner, K. Schauenstein, R. Windhager
- Chemistry, Medicine
- Osteoarthritis and cartilage
- 1 November 2007
OBJECTIVE Physical cues play a crucial role in skeletogenesis and osteochondral regeneration. Although human mesenchymal stem cells (hMSCs) offer considerable therapeutic potential, little is known… Expand
Immunohistochemical analysis of desmoid tumours
- A. Leithner, M. Gapp, +5 authors A. Beham
- Biology, Medicine
- Journal of Clinical Pathology
- 1 November 2005
Background/Aims: Although the standard treatment for desmoid tumours is complete surgical resection with wide margins, the optimal adjuvant treatment for recurrent or inoperable disease is unclear,… Expand