R. Winchester

Publications189
h-index66
Citations29,215
Highly Influential Citations684
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The 1982 revised criteria for the classification of systemic lupus erythematosus.
The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification. The… Expand
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The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis.
Aucun gene HLA seul n'a ete identifie comme conferant un risque de maladie. Distinction et definition des sous-types DR4. Role de la 3eme region hypervariable de DRβ1. Relation entre risque de… Expand
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Reprogramming of CTLs into natural killer–like cells in celiac disease
Celiac disease is an intestinal inflammatory disorder induced by dietary gluten in genetically susceptible individuals. The mechanisms underlying the massive expansion of interferon γ–producing… Expand
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HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype.
OBJECTIVE Rigorously ascertained cases of psoriatic arthritis in subjects presenting to a rheumatology unit were compared with cases of psoriasis in subjects presenting to a dermatology unit, where… Expand
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Psoriatic arthritis: from pathogenesis to therapy
Psoriatic arthritis is a multigenic autoimmune disease that involves synovial tissue, entheseal sites and skin, and that may result in significant joint damage. Although there are no diagnostic tests… Expand
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Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells
Human T-cell blasts were generated by stimulation with mitogens and antigens. A proportion of these blasts expressed Ia antigens detectable by immunofluorescence with both allo- and… Expand
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Treatment of Lupus Nephritis With Abatacept: The Abatacept and Cyclophosphamide Combination Efficacy and Safety Study
To assess the efficacy and safety of a 24‐week course of abatacept in the treatment of active lupus nephritis and to assess the potential of abatacept to induce “clinical tolerance,” defined as… Expand
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THE FINE STRUCTURE OF THE GASTRIC MUCOSA IN THE BAT
A description of the cytology of the gastric mucosa is presented based upon an electron microscopic investigation of the bat stomach. The fine structure of the various cell types in this species is… Expand
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C1q PRECIPITINS IN THE SERA OF PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND OTHER HYPOCOMPLEMENTEMIC STATES: CHARACTERIZATION OF HIGH AND LOW MOLECULAR WEIGHT TYPES
Precipitin reactions of C1q in gel diffusion proved useful in detecting unknown complexes containing γ-globulin in the sera of patients with SLE. Using this method low molecular weight C1q reactants… Expand
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The molecular basis of susceptibility to rheumatoid arthritis.
Publisher Summary This chapter discusses the development, current understanding, and some of the implications of the molecular basis of susceptibility to rheumatoid arthritis as it relates to the… Expand
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