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Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial.
CONTEXT Alcohol dependence treatment may include medications, behavioral therapies, or both. It is unknown how combining these treatments may impact their effectiveness, especially in the context ofExpand
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Functional magnetic resonance imaging of human brain activation during cue-induced cocaine craving.
OBJECTIVE Functional magnetic resonance imaging (MRI) was used to test whether brain activation was detectable in regions previously associated with cocaine cue-induced craving. METHOD BloodExpand
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The role of therapist adherence, therapist competence, and alliance in predicting outcome of individual drug counseling: Results from the National Institute Drug Abuse Collaborative Cocaine Treatment
Abstract This study tested hypotheses related to linear and curvilinear relations among adherence, competence, and outcome and interactions of these effects with the quality of the therapeuticExpand
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Self-help organizations for alcohol and drug problems: toward evidence-based practice and policy.
This expert consensus statement reviews evidence on the effectiveness of drug and alcohol self-help groups and presents potential implications for clinicians, treatment program managers andExpand
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Adjunctive counseling during brief and extended buprenorphine-naloxone treatment for prescription opioid dependence: a 2-phase randomized controlled trial.
CONTEXT No randomized trials have examined treatments for prescription opioid dependence, despite its increasing prevalence. OBJECTIVE To evaluate the efficacy of brief and extended buprenorphineExpand
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“Seeking Safety”: Outcome of a New Cognitive-Behavioral Psychotherapy for Women with Posttraumatic Stress Disorder and Substance Dependence
Women with current posttraumatic stress disorder (PTSD) comprise 30–59% of substance abuse treatment samples and experience a more severe course than women with either disorder alone. As yet, noExpand
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Medical morbidity, mental illness, and substance use disorders.
OBJECTIVE Previous research on the prevalence of medical disorders among adults with mental illness has been inconclusive. In general, studies have found higher rates among persons with mentalExpand
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Prospective 12-month course of bipolar disorder in out-patients with and without comorbid anxiety disorders
Background The impact of anxiety disorders has not been well delineated in prospective studies of bipolar disorder. Aims To examine the association between anxiety and course of bipolar disorder, asExpand
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A comparison of male and female cocaine abusers.
Little has been written about the differences between male and female cocaine abusers. We therefore compared sociodemographic characteristics, reasons for cocaine use, drug effects, depressiveExpand
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Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations.
CONTEXT The 5-HTTLPR polymorphism in the promoter region of the serotonin transporter gene (SLC6A4) has been found to moderate several categories of emotional response after stressful life events.Expand
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