• Publications
  • Influence
Nature’s hierarchical materials
Abstract Many biological tissues, such as wood and bone, are fiber composites with a hierarchical structure. Their exceptional mechanical properties are believed to be due to a functional adaptationExpand
  • 1,596
  • 35
  • Open Access
Architecture of the osteocyte network correlates with bone material quality
In biological tissues such as bone, cell function and activity crucially depend on the physical properties of the extracellular matrix which the cells synthesize and condition. During bone formationExpand
  • 215
  • 11
The bone mineralization density distribution as a fingerprint of the mineralization process.
The inhomogeneous mineral content and its topographical distribution on a microscopic scale are major determinants of the mechanical quality of trabecular bone. The kinetics of bone tissue depositionExpand
  • 181
  • 8
The Periosteal Bone Surface is Less Mechano-Responsive than the Endocortical
Dynamic processes modify bone micro-structure to adapt to external loading and avoid mechanical failure. Age-related cortical bone loss is thought to occur because of increased endocorticalExpand
  • 41
  • 5
Mechanical properties of micro-and nanocapsules : Single-capsule measurements
Abstract Capsules of micron and sub-micron dimensions are abundant in nature in the form of bacterial or viral capsids and play an increasing role in modern technology for encapsulation and releaseExpand
  • 193
  • 4
  • Open Access
Mechanical adaptation of biological materials — The examples of bone and wood
Abstract Many biological materials have the property of being responsive to their environment combined with the ability to adapt to possible changes in this environment. Two prototypical responsiveExpand
  • 75
  • 4
The influence of age on adaptive bone formation and bone resorption.
Bone is a tissue with enormous adaptive capacity, balancing resorption and formation processes. It is known that mechanical loading shifts this balance towards an increased formation, leading toExpand
  • 57
  • 3
Structural Adaptation of Trabecular Bone Revealed by Position Resolved Analysis of Proximal Femora of Different Primates
The anisotropic arrangement of trabeculae in the proximal femur of humans and primates is seen as striking evidence for the functional adaptation of trabecular bone architecture. QuantitativeExpand
  • 26
  • 3
Mechanical Properties of Freestanding Polyelectrolyte Capsules : a Quantitative Approach Based on Shell Theory
In this paper we report on AFM force spectroscopy measurements on hollow polymeric spheres of colloidal dimensions made from polyelectrolyte multilayers of polyallylamine and polystyrenesulfonate inExpand
  • 49
  • 3
Spatial heterogeneity in the canalicular density of the osteocyte network in human osteons
Osteocytes interconnect with each other forming an intricate cell network within the mineralized bone matrix. One important function of the osteocyte network is the mechano-regulation of boneExpand
  • 26
  • 3