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Microarray Analysis of the Nitrate Response in Arabidopsis Roots and Shoots Reveals over 1,000 Rapidly Responding Genes and New Linkages to Glucose, Trehalose-6-Phosphate, Iron, and Sulfate
The results show that the effect of nitrate on gene expression is substantial yet selective and affects many genes involved in carbon and nutrient metabolism, including enzymes in glycolysis, metabolism, and iron transport/metabolism. Expand
Genomic Analysis of the Nitrate Response Using a Nitrate Reductase-Null Mutant of Arabidopsis1[w]
A nitrate reductase (NR)-null mutant of Arabidopsis was constructed that had a deletion of the major NR gene NIA2 and an insertion in the NIA1 NR gene, and there was substantial organ specificity to the nitrate response. Expand
A Genetic Screen for Nitrate Regulatory Mutants Captures the Nitrate Transporter Gene NRT1.11[W][OA]
Genes involved in nitrate assimilation, energy metabolism, and pentose-phosphate pathway were most affected and strongly support the model that NRT1.1 acts as a nitrate regulator or sensor in Arabidopsis. Expand
Nitrite Acts as a Transcriptome Signal at Micromolar Concentrations in Arabidopsis Roots1[W][OA]
Nitrate serves as a potent signal to control gene expression in plants and algae, but little is known about the signaling role of nitrite, the direct product of nitrate reduction. Analysis of severalExpand
Nitrate foraging by Arabidopsis roots is mediated by the transcription factor TCP20 through the systemic signaling pathway
These studies demonstrate that the transcription factor TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR1-20 (TCP20) functions in nitrate foraging as an essential part of the systemic signaling pathway that redirects root growth to nitrate-rich zones. Expand
AtNIGT1/HRS1 integrates nitrate and phosphate signals at the Arabidopsis root tip
It is proposed that NO3− and P signaling converge via double transcriptional and post-transcriptional control of the same protein, HRS1, and it is demonstrated that this transcription factor and a close homolog repress primary root growth in response to P deficiency conditions, but only whenNO3− is present. Expand
The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators[OPEN]
Genetic and molecular data suggest that NRG2 plays a key role in nitrate regulation in part through modulating NRT1.1 expression and may function with NLP7 via their physical interaction. Expand
Insights into the genomic nitrate response using genetics and the Sungear Software System.
The use of an Arabidopsis NR-null mutant allowed the identification of genes that respond to nitrate when the production of downstream metabolites of nitrate is blocked, suggesting these latter processes may be regulated by downstream nitrogen metabolites. Expand
The Arabidopsis dual-affinity nitrate transporter gene AtNRT1.1 (CHL1) is regulated by auxin in both shoots and roots.
It was found that treatment with exogenous auxin or introduction of the auxin overproducing mutations resulted in a strong increase in CHL1::GUS/GFP signals in roots and leaves, and this results indicate that auxin acts as an important signal regulatingCHL1 expression and contributes to the targeting of CHL 1 expression to nascent organs and root tips in Arabidopsis. Expand
Multiple Regulatory Elements in the Arabidopsis NIA1 Promoter Act Synergistically to Form a Nitrate Enhancer1[W][OA]
A cis-regulatory module containing three elements that comprise a nitrate enhancer in the NIA1 promoter is identified and validated in transgenic Arabidopsis plants. Expand