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Paroxysmal supraventricular tachycardia in the general population.
TLDR
The data suggest etiologic heterogeneity in the pathogenesis of PSVT and the need for more population-based research on this common condition. Expand
Benign breast disease and the risk of breast cancer.
TLDR
Risk factors for breast cancer after the diagnosis of benign breast disease include the histologic classification of a benign breast lesion and a family history of breast cancer. Expand
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
TLDR
Using the Illumina custom genotyping array iCOGs, SNPs at the TERT locus in breast, ovarian and BRCA1 mutation carrier cancer cases and controls and leukocyte telomere measurements are analyzed to find associations cluster into three independent peaks. Expand
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study.
TLDR
Clinical trials, stratified by subtype and biomarker status, are needed to establish whether hormone-receptor status predicts response to endocrine treatment, and whether it could guide personalised treatment for ovarian cancer. Expand
Risk factors for carpal tunnel syndrome in a general population.
TLDR
Cpal tunnel syndrome is a work related disease, although some important measures of occupational exposure, including keyboard use, were not risk factors in this general population study. Expand
Benign breast disease and the risk of breast cancer.
TLDR
Risk factors for breast cancer after the diagnosis of benign breast disease include the histologic classification of a benign breast lesion and a family history of breast cancer. Expand
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
TLDR
Nine additional candidate loci are reported on and analysis of HOXD1, MYC, TIPARP and SKAP1 at these loci and of BNC2 at 9p22 supports a functional role for these genes in ovarian cancer development. Expand
Stratification of breast cancer risk in women with atypia: a Mayo cohort study.
TLDR
Among women with atypical hyperplasia, multiple foci of atypia and the presence of histologic calcifications may indicate "very high risk" status (> 50% risk at 20 years). Expand
Incidence and predictors of atrial flutter in the general population.
TLDR
This study, the first population-based investigation of atrial flutter, suggests this curable condition is much more common than previously appreciated and if the findings were applicable to the entire U.S. population, it is estimated 200,000 new cases of atrian flutter in this country annually. Expand
Interaction of waist/hip ratio and family history on the risk of hormone receptor-defined breast cancer in a prospective study of postmenopausal women.
TLDR
The previously reported interaction between family history and waist/hip ratio is still (weakly) evident and appears to reflect risk for progesterone receptor-negative tumors. Expand
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