Author pages are created from data sourced from our academic publisher partnerships and public sources.
The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4.
- A. Kubo, K. Nakagawa, +7 authors M. Kelley
- Biology, Medicine
- Clinical cancer research : an official journal of…
- 1 December 1999
Loss of p16 functional activity leading to disruption of the p16/cyclin-dependent kinase (CDK) 4:cyclin D/retinoblastoma pathway is the most common event in human tumorigenesis, suggesting that… Expand
Synthesis of analogs of 2-methoxyestradiol with enhanced inhibitory effects on tubulin polymerization and cancer cell growth.
- M. Cushman, H. He, +5 authors Y. P. Sachdeva
- Chemistry, Medicine
- Journal of medicinal chemistry
- 18 July 1997
A new series of estradiol analogs was synthesized in an attempt to improve on the anticancer activity of 2-methoxyestradiol, a naturally occurring mammalian tubulin polymerization inhibitor. The… Expand
Evaluation of dimethyl sulfoxide as a solvent in pharmacological experiments.
Design and Synthesis of Ellipticinium Salts and 1,2‐ Dihydroellipticines with High Selectivities against Human CNS Cancers in Vitro.
Right Dorsolateral Frontal Lobe N-Acetyl Aspartate and Myoinositol Concentration Estimation in Type 2 Diabetes with Magnetic Resonance Spectroscopy.
- R. S. Nagothu, Yogananda Indla Reddy, Archana Rajagopalan, R. Varma
- Journal of clinical and diagnostic research…
- 1 July 2015
INTRODUCTION Chronic hyperglycaemia in type 2 diabetes, effects the central nervous system by altering the concentrations of brain metabolites like N-acetyl aspartate (NAA) and myoinositol (mI),… Expand
Low-level beta activity measurement of solid samples using plastic scintillator anticoincidence
Abstract An instrument consisting of a G.M. counter shieded by a plastic-scintillator-cone and 15 cm of lead has been designed giving a background of 12 counts per hour. The sample spread in an area… Expand
Supernumerary tooth in palate--a case report.
New reagents for stereoselective carbonyl reduction. An improved synthetic route to the primary prostaglandins.
Specific reduction of E prostaglandins to F.alpha. prostaglandins and prostaglandin E2 to prostaglandin E1
This is an explanation of 2 highly specific reductive processes for the interconversion of primary PGs (prostaglandins). The laboratory procedures are described in detail and the chemical structures… Expand
Efficient generation of the 15S configuration in prostaglandin synthesis. Attractive interactions in stereochemical control of carbonyl reduction.