• Publications
  • Influence
Clinical practice guideline on diagnosis and treatment of hyponatraemia.
TLDR
The Clinical Practice Guideline on the diagnostic approach and treatment of hyponatraemia is developed as a joint venture of three societies representing specialists with a natural interest in hyponatonemia to obtain a common and holistic view. Expand
Review on uremic toxins: classification, concentration, and interindividual variability.
TLDR
Concentrations of retention solutes in uremia vary over a broad range, from nanograms per liter to grams per liter, and a substantial number of molecules are protein bound and/or middle molecules, and many of these exert toxicity and are characterized by a high range of toxic over normal concentration (CU/CN ratio). Expand
Acute kidney injury: an increasing global concern
TLDR
Developing or progression of chronic kidney disease after one or more episode of acute kidney injury could have striking socioeconomic and public health outcomes for all countries. Expand
International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology
Executive summary Acute kidney injury (AKI) is a major contributor to poor patient outcomes. AKI occurs in about 13·3 million people per year, 85% of whom live in the developing world, and, althoughExpand
Normal and pathologic concentrations of uremic toxins.
TLDR
A literature search found 621 articles about uremic toxicity published after a 2003 review of this topic and found most solutes (59%) in only one report, which should aid the design of experiments to study the biologic effects of these solutes in CKD. Expand
EBPG guideline on nutrition.
TLDR
Recommendations for vitamins,minerals and trace elementsadministration in maintenancehaemodialysis patients and other interventions: daily dialysis, oral supplements and enteral feeding. Expand
Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease*
TLDR
The establishment of a reproducible, high resolution method for peptidome analysis of naturally occurring human urinary peptides and proteins, ranging from 800 to 17,000 Da, using samples from 3,600 individuals analyzed by capillary electrophoresis coupled to MS is reported. Expand
The uremic toxicity of indoxyl sulfate and p-cresyl sulfate: a systematic review.
TLDR
A systematic approach allowed the retrieval of methodologically correct studies unbiased by erroneous conditions related to albumin binding, and the data seem to confirm the toxicity of indoxyl sulfate and p-cresyl sulfates and support their roles in vascular and renal disease progression. Expand
Acute renal failure
TLDR
Some basic and recent insights into the haemodynamic and cellular pathophysiological mechanisms, mainly of postischaemic acute renal failure, are summarised. Expand
The burden of kidney disease: improving global outcomes.
TLDR
A new initiative "Kidney Disease: Improving Global Outcomes" has been established, its stated mission is to improve the care and outcomes of kidney disease patients worldwide through promoting coordination, collaboration and integration of initiatives to develop and implement clinical practice guidelines. Expand
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