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Brominated flame retardants and perfluorinated chemicals, two groups of persistent contaminants in Belgian human blood and milk.
We assessed the exposure of the Flemish population to brominated flame retardants (BFRs) and perfluorinated compounds (PFCs) by analysis of pooled cord blood, adolescent and adult serum, and humanExpand
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Exposure of the Flemish population to brominated flame retardants: model and risk assessment.
Human exposure to brominated flame retardants (BFRs) varies widely throughout the world as it depends on country-related usage, production and legislation of these chemicals. US and UK exposureExpand
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Immunologic biomarkers in relation to exposure markers of PCBs and dioxins in Flemish adolescents (Belgium).
In this study, we investigated 17- to 18-year-old boys and girls to determine whether changes in humoral or cellular immunity or respiratory complaints were related to blood serum levels ofExpand
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Induction of Oral Tolerance to Oxidized Low-Density Lipoprotein Ameliorates Atherosclerosis
Background— Oxidation of low-density lipoprotein (LDL) and the subsequent processing of oxidized LDL (oxLDL) by macrophages results in activation of specific T cells, which contributes to theExpand
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A new approach to study exhaled proteins as potential biomarkers for asthma
Cite this as: K. Bloemen, R. Van Den Heuvel, E. Govarts, J. Hooyberghs, V. Nelen, E. Witters, K. Desager and G. Schoeters, Clinical & Experimental Allergy, 2011 (41) 346–356.
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Use of in vitro assays to assess hematotoxic effects of environmental compounds
AbstractThe number of chemicals being introduced into the environment increases and many of these substances may pose a health risk to exposed individuals. Many environmental toxicants with aExpand
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Gene expression signatures in CD34+-progenitor-derived dendritic cells exposed to the chemical contact allergen nickel sulfate.
The detection of the sensitizing potential of chemicals is of great importance to industry. A promising in vitro alternative to the currently applied animal assays for sensitization testing makes useExpand
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Modulation of phenotype, cytokine production and stimulatory function of CD34+-derived DC by NiCl(2) and SDS.
One of the most promising alternatives to identify the sensitizing potency of new products is the in vitro culture of human dendritic cells (DC). In vivo, dendritic cells present in the skin areExpand
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Microarray analyses in dendritic cells reveal potential biomarkers for chemical-induced skin sensitization.
The assessment of the skin sensitising capacity of chemicals is up to now investigated using in vivo animal tests. However there has been an increasing public and governmental concern regarding theExpand
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Interleukin-10 inhibits the osteogenic activity of mouse bone marrow.
Murine bone marrow cells synthesize bone proteins, including alkaline phosphatase (ALP), collagen type I, and osteocalcin, and form a mineralized extracellular matrix when cultured in the presence ofExpand
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