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- Publications
- Influence
Immune Responses in Healthy and Allergic Individuals Are Characterized by a Fine Balance between Allergen-specific T Regulatory 1 and T Helper 2 Cells
- M. Akdis, J. Verhagen, +12 authors C. Akdis
- Biology, Medicine
- The Journal of experimental medicine
- 7 June 2004
The mechanisms by which immune responses to nonpathogenic environmental antigens lead to either allergy or nonharmful immunity are unknown. Single allergen-specific T cells constitute a very small… Expand
Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal
- P. Valent, C. Akin, +16 authors D. Metcalfe
- Medicine
- International Archives of Allergy and Immunology
- 2011
Activation of tissue mast cells (MCs) and their abnormal growth and accumulation in various organs are typically found in primary MC disorders also referred to as mastocytosis. However, increasing… Expand
Allergen immunotherapy: therapeutic vaccines for allergic diseases
- J. Bousquet, R. Lockey, +19 authors H. Yssel
- Medicine
- 1 November 1998
ABBREVIATIONS AAAAI: American Academy of Allergy, Asthma and Immunology AU: Allergy Unit BAU: Bioequivalent Allergy Unit BU: Biologic Unit CBER: Center for Biologic Evaluation and Research EAACI:… Expand
Release of allergens as respirable aerosols: A link between grass pollen and asthma.
- P. E. Taylor, R. Flagan, R. Valenta, M. Glovsky
- Biology, Medicine
- The Journal of allergy and clinical immunology
- 2002
BACKGROUND
Asthma incidence has long been linked to pollen, even though pollen grains are too large to penetrate into the airways where asthmatic responses originate. Pollen allergens found in small,… Expand
Analysis of the sensitization profile towards allergens in central Africa
- K. Westritschnig, E. Sibanda, +7 authors R. Valenta
- Medicine
- Clinical and experimental allergy : journal of…
- 1 January 2003
Background Almost no information is available regarding the prevalence of IgE‐mediated allergies and the disease‐eliciting allergens in tropical Africa.
The gene coding for the major birch pollen allergen Betv1, is highly homologous to a pea disease resistance response gene.
- H. Breiteneder, K. Pettenburger, +5 authors M. Breitenbach
- Biology, Medicine
- The EMBO journal
- 1 July 1989
Pollen of the white birch (Betula verrucosa) is one of the main causes of Type I allergic reactions (allergic rhinoconjunctivitis, allergic bronchial asthma) in Middle and Northern Europe, North… Expand
Microinjected profilin affects cytoplasmic streaming in plant cells by rapidly depolymerizing actin microfilaments
- C. Staiger, M. Yuan, R. Valenta, P. Shaw, C. Lloyd
- Biology, Medicine
- Current Biology
- 1 March 1994
BACKGROUND
Cytoplasmic streaming is a conspicuous feature of plant cell behaviour, in which organelles and vesicles shuttle along cytoplasmic strands that contain actin filaments. The mechanisms that… Expand
FcepsilonRI engagement of Langerhans cell-like dendritic cells and inflammatory dendritic epidermal cell-like dendritic cells induces chemotactic signals and different T-cell phenotypes in vitro.
- N. Novak, R. Valenta, +4 authors T. Bieber
- Biology, Medicine
- The Journal of allergy and clinical immunology
- 1 May 2004
BACKGROUND
Atopic dermatitis (AD) is a biphasic inflammatory skin disease characterized by an initial phase predominated by T(H)2 cytokines, which switches into a second T(H)1-dominated chronic… Expand
Identification of profilin as a novel pollen allergen; IgE autoreactivity in sensitized individuals.
- R. Valenta, M. Duchêne, +7 authors O. Scheiner
- Biology, Medicine
- Science
- 2 August 1991
A complementary DNA encoding a pollen allergen from white birch (Betula verrucosa) that was isolated from a pollen complementary DNA library with serum immunoglobulin E from a birch pollen-allergic… Expand
Identification of common allergenic structures in hazel pollen and hazelnuts: a possible explanation for sensitivity to hazelnuts in patients allergic to tree pollen.
- R. Hirschwehr, R. Valenta, +7 authors D. Kraft
- Biology, Medicine
- The Journal of allergy and clinical immunology
- 1 December 1992
It is known that most patients with type I allergy to tree pollens also suffer from intolerance to nuts. To identify allergenic structures common to hazel pollen and hazelnuts, cross-reactivity of… Expand