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Molecular mechanisms of neuronal dense core vesicle release
door Rhea van de Bospoort geboren te Zaandam
Munc18-1 and Munc18-2 are required for efficient neuropeptide secretion in DIV14 hippocampal neu- rons
Sec1/Munc18 (SM) proteins are essential for SNARE-dependent vesicle fusion. In the brain, three Munc18 isoforms (Munc18-1, -2, and -3) are expressed. Synaptic vesicle fusion is abolished in theExpand
Abstract 986: High content analysis of 2D and 3D oncology models for target and phenotypic drug discovery
Charles River (CR) has developed many disease-relevant cellular models to screen small molecules and genetic modifiers for target and phenotypic based drug discovery. Our expertise and portfolio inExpand
Activation of TrkB signaling pathway by TrkB mAbs.