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BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer.
In patients with PTC, BRAF mutation is associated with poorer clinicopathological outcomes and independently predicts recurrence, and may be a useful molecular marker to assist in risk stratification for patients withPTC. Expand
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer.
In this retrospective multicenter study, the presence of the BRAF V600E mutation was significantly associated with increased cancer-related mortality among patients with PTC, and the association was not independent of tumor features. Expand
Consensus statement on the terminology and classification of central neck dissection for thyroid cancer.
Central neck dissection at a minimum should consist of removal of the prelaryngeal, pretracheal, and paratracheAL lymph nodes. Expand
Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer
The results suggest that aberrant methylation and hence silencing of TIMP3, SLC5A8, DAPK and RARβ2, in association with BRAF mutation, may be an important step in PTC tumorigenesis and progression. Expand
Cystic lymph node metastasis in patients with head and neck cancer: An HPV‐associated phenomenon
The clinical and virologic associations of cystic nodal metastasis in head and neck cancer (HNSCC) were investigated and cystic lymph node metastases were associated with tonsil cancer. Expand
BRAF mutation testing of thyroid fine-needle aspiration biopsy specimens for preoperative risk stratification in papillary thyroid cancer.
Preoperative BRAF mutation testing of FNAB specimens provides a novel tool to preoperatively identify PTC patients at higher risk for extensive disease and those who are more likely to manifest disease persistence/recurrence. Expand
Mutational Analysis of BRAF in Fine Needle Aspiration Biopsies of the Thyroid: A Potential Application for the Preoperative Assessment of Thyroid Nodules
A BRAF mutation can be reliably detected in cells aspirated from a thyroid nodule suggesting a role for this marker in the preoperative evaluation of thyroid nodules. Expand
Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.
Almost 90% of MTCs had mutually exclusive mutations in RET, HRAS, and KRAS, suggesting that RET and RAS are the predominant driver pathways in MTC. Expand
American Thyroid Association statement on outpatient thyroidectomy.
Outpatient thyroidectomy may be undertaken safely in a carefully selected patient population provided that certain precautionary measures are taken to maximize communication and minimize the likelihood of complications. Expand
Safety of robotic thyroidectomy approaches: Meta‐analysis and systematic review
This study compared the efficacy of robotic thyroidectomy via a gasless, axillary approach with conventional cervical and endoscopic techniques by meta‐analysis.