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Dried blood spot real-time polymerase chain reaction assays to screen newborns for congenital cytomegalovirus infection.
CONTEXT Reliable methods to screen newborns for congenital cytomegalovirus (CMV) infection are needed for identification of infants at increased risk of hearing loss. Since dried blood spots (DBS)… Expand
Functional and histological characteristics of skeletal muscle and the effects of leptin in the genetically obese (ob/ob) mouse
BACKGROUND: Skeletal muscle mass in genetically obese (ob/ob) mice displays a reduced mass compared with their normal lean counterpart mice. However, the functional capacity of the available skeletal… Expand
Mixed infection and strain diversity in congenital cytomegalovirus infection.
BACKGROUND Cytomegalovirus (CMV), the most common cause of congenital infection, exhibits extensive genetic variability. We sought to determine whether multiple CMV strains can be transmitted to the… Expand
Saliva polymerase-chain-reaction assay for cytomegalovirus screening in newborns.
BACKGROUND Congenital cytomegalovirus (CMV) infection is an important cause of hearing loss, and most infants at risk for CMV-associated hearing loss are not identified early in life because of… Expand
Fascioliasis Due to Fasciola hepatica and Fasciola gigantica Infection: An Update on This ‘Neglected’ Neglected Tropical Disease
- Robert W. Tolan
- 1 February 2011
Fascioliasis, an infection due to the food- and water-borne trematodes Fasciola hepatica and Fasciola gigantica, is among the most neglected of the neglected tropical diseases. Among the estimated… Expand
Probable Congenital Babesiosis in Infant, New Jersey, USA
- Sonia Sethi, David Alcid, H. Kesarwala, R. Tolan
- Biology, Medicine
- Emerging infectious diseases
- 1 May 2009
Only 2 neonates with transplacentally or perinatally acquired (congenital) babesiosis have been reported. We describe a probable third congenital case of babesiosis in a 26-day-old infant;… Expand
Fever of Unknown Origin: A Diagnostic Approach to This Vexing Problem
- R. Tolan
- Clinical pediatrics
- 1 March 2010
Fever is a common complaint leading families to seek medical attention. Its routine management is the bread and butter of pediatric practice. When fever is seen as prolonged beyond the expected time… Expand
Comparison of Saliva Pcr Assay Versus Rapid Culture for Detection of Congenital Cytomegalovirus Infection
- S. Pinninti, S. Ross, +9 authors S. Boppana
- The Pediatric infectious disease journal
- 1 May 2015
As part of the CMV and Hearing Multicenter Screening (CHIMES) study, 72,239 newborns were screened for cytomegalovirus by rapid culture and real-time PCR of saliva samples. Of the 266 infants with… Expand
An Adolescent With Pseudomigraine, Transient Headache, Neurological Deficits, and Lymphocytic Pleocytosis (HaNDL Syndrome)
We report a 16-year-old adolescent with 2 episodes of focal neurological deficits, pseudomigrainous headache, and lymphocytic pleocytosis due to the syndrome of transient headache and neurological… Expand
Infertility, in vitro fertilization and congenital tuberculosis
Congenital tuberculosis (CTB) due to maternal genitourinary (GU) TB infection is a rare occurrence, as infection of the genital tract in women generally leads to infertility. Increasing availability… Expand