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Drosophila Neuroligin 1 Promotes Growth and Postsynaptic Differentiation at Glutamatergic Neuromuscular Junctions
Precise apposition of presynaptic and postsynaptic domains is a fundamental property of all neuronal circuits. Experiments in vitro suggest that Neuroligins and Neurexins function as key regulatoryExpand
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Mapping quantitative trait loci underlying the cooking and eating quality of rice using a DH population
The cooking and eating quality of rice has attracted more attention recently. In a comprehensive effort to unravel its genetic basis, we conducted a genome-wide analysis of six traits representingExpand
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Pancreatic Cancer Cells Resistant to Chemoradiotherapy Rich in “Stem-Cell-Like” Tumor Cells
BackgroundTumor resistance to chemoradiation therapy is partly attributed to the presence of apoptosis-resistant cancer stem cells (CSCs). Chemoradiation therapy can enrich CSCs by killingExpand
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Peptides that regulate food intake: appetite-inducing accumbens manipulation activates hypothalamic orexin neurons and inhibits POMC neurons.
Corticolimbic circuits involving the prefrontal cortex, amygdala, and ventral striatum determine the reward value of food and might play a role in environmentally induced obesity. ChemicalExpand
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Solute Geochemistry and Multivariate Analysis of Water Quality in the Guohua Phosphorite Mine, Guizhou Province, China
Water plays a critical role in securing the mine production and domestic consumption in mining areas. This research was carried out to assess the water quality status and to identify theExpand
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Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells.
Application of oxaliplatin for the treatment of pancreatic cancer (PC) is restricted owing to its toxic side effects and drug resistance. We investigated how withaferin A (WA), a bioactive componentExpand
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CD44+CD133+ population exhibits cancer stem cell-like characteristics in human gallbladder carcinoma
Cancer stem cells (CSCs)/tumor-initiating cells have been defined as a subset of tumor cells responsible for initiating and sustaining tumor development. Emerging evidence strongly supports theExpand
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Spatiotemporal Variability of Contaminants in Lake Water and Their Risks to Human Health: A Case Study of the Shahu Lake Tourist Area, Northwest China
Shahu Lake is a well-known tourist lake in Ningxia, northwest China. This study analyzed the general hydrochemical characteristics of the lake water to determine the spatiotemporal variability ofExpand
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A Genomic Encyclopedia of the Root Nodule Bacteria: assessing genetic diversity through a systematic biogeographic survey
Root nodule bacteria are free-living soil bacteria, belonging to diverse genera within the Alphaproteobacteria and Betaproteobacteria, that have the capacity to form nitrogen-fixing symbioses withExpand
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A presynaptic role for the cytomatrix protein GIT in synaptic vesicle recycling.
Neurotransmission involves the exo-endocytic cycling of synaptic vesicles (SVs) within nerve terminals. Exocytosis is facilitated by a cytomatrix assembled at the active zone (AZ). The preciseExpand
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