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MAC of 1–653 in Beagle Dogs and New Zealand White Rabbits
TLDR
The minimum alveolar concentration (MAC) of 1–653 was determined in six beagle dogs and four New Zealand white rabbits and comparison of these results with published MAC values for other anesthetics indicate that 1-653 is likely to be low. Expand
MAC of I-653 in beagle dogs and New Zealand white rabbits.
TLDR
Comparison of these results with published MAC values for other anesthetics indicate that I-653 is one-third to one-eighth as potent as currently available volatileAnesthetics (enflurane, isofluranes, and halothane). Expand
Minimum Alveolar Concentrations and Oil/Gas Partition Coefficients of Four Anesthetic Isomers
TLDR
The results suggest that isomer 485, despite its high MAC, does not deviate strikingly from the established correlation between anesthetic potency and lipid solubility. Expand
Are convulsant gases also anesthetics
TLDR
The increase of isoflurane requirement at lower concentrations of flurothyl suggests that anesthetics with a potential to cause convulsions may partly antagonize their own anesthetic effect. Expand
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