Author pages are created from data sourced from our academic publisher partnerships and public sources.
Share This Author
Angiogenesis-dependent tumor spread in reinforced fibrin clot culture.
To investigate the role played by developing microvessels in the spread of tumors, segments of rat aorta were cultured with aggregates of NBT-II-81, a cell line derived from squamous cell carcinoma…
The chick embryo in toxicology: an alternative to the rabbit eye.
Role of biotransformation in 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione-induced hepatotoxicity in Fischer 344 rats.
Maturational changes in CYP2D16 expression and xenobiotic metabolism in adrenal glands from male and female guinea pigs.
- B. Yuan, R. Tchao, J. Voigt, H. Colby
- Biology, MedicineDrug metabolism and disposition: the biological…
- 1 February 2001
Results indicate that the age and gender differences in adrenal CYP2D16 content are largely determined by differences in the size of the ZR rather than the concentrations of CYP 2D16 within cells of theZR, however, adrenal xenobiotic-metabolizing activities in females seem to be further modulated by an inhibitory effect of estrogens.
Hemicyst formation stimulated by cyclic AMP in dog kidney cell line MDCK
C cultured epithelial cells may provide an exploitable model system to investigate at the cellular and subcellular levels, the mechanism by which cyclic AMP modifies water and solute movements across epithelia.
Interactions of tumor cells with human amnion membrane: a model for studying tumor invasion in vitro.
These ultrastructural findings show, that the amnion membrane model allows morphological analysis of various steps of tumor invasion under standardized conditions.
Histotypic angiogenesis in vitro: Light microscopic, ultrastructural, and radioautographic studies
This experimental model, histophysiologic gradient culture, provides a new tool for the study of vascular morphogenesis, angiogenesis dependent growth of tumors, and neoplastic intravasation.
Use of a Human Corneal Epithelial Cell Line for Screening the Safety of Contact Lens Care Solutions In Vitro
- D. McCanna, K. Harrington, J. Driot, K. Ward, R. Tchao
- Medicine, BiologyEye & contact lens
- 1 January 2008
The sodium fluorescein permeability assay, alamarBlue assay, and scanning electron microscopy showed that OPTI-FREE Express was significantly more damaging to the human corneal epithelial cell monolayer than ReNu MultiPlus, SOLO-care Plus With Aqualube, Complete Moisture Plus, and AQuify 5 Minute contact lens solutions.
Effect of Processing Methods and Heat Treatment on the Formation of Wax Matrix Tablets for Sustained Drug Release
- Y. Zhang, R. Tchao, J. Schwartz
- Materials Science, ChemistryPharmaceutical development and technology
- 1 January 2001
Evaluating the effects of processing methods and heat treatment on matrix formation and subsequent drug release from wax matrix tablets for controlled release indicated that heat treatment caused the wax to melt, redistribute, coat the drug and diluents, and form a network structure.
Comparison of contact lens multipurpose solutions by in vitro sodium fluorescein permeability assay.
- R. Tchao, D. McCanna, Michael J. Miller
- Medicine, BiologyThe CLAO journal : official publication of the…
- 1 July 2002
In vitro sodium fluorescein permeability assay can be used to determine the effect that various contact lens disinfecting products have on the integrity of an epithelium in culture, and Cultures treated with the two OPTIFREE Express solutions were more permeable to sodium fluorscein than cultures treating with the other multipurpose solutions.