• Publications
  • Influence
Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition
TLDR
The scope and purpose of this work is to synthesize the available evidence and to translate it into recommendations, so that these recommendations be used by others to develop treatment protocols, which necessarily need to incorporate consensus and clinical judgment in areas where current evidence is lacking or insufficient.
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents--second edition.
TLDR
This review highlights the need to understand more fully the rationale behind the rapid decline in response to certain types of head injuries in children with severe brain injuries.
ESPE/LWPES consensus statement on diabetic ketoacidosis in children and adolescents
TLDR
There is debate as to whether physicians treating DKA can prevent or predict the occurrence of cerebral oedema, and the appropriate site(s) for children with DKA to be managed.
Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children
TLDR
A large cohort of international experts was able to achieve consensus regarding many recommendations for the best care of children with sepsis, acknowledging that most aspects of care had relatively low quality of evidence resulting in the frequent issuance of weak recommendations.
European Society for Paediatric Endocrinology/Lawson Wilkins Pediatric Endocrine Society consensus statement on diabetic ketoacidosis in children and adolescents.
TLDR
The Consensus statement was developed with close partnership between the ESPE and LWPES and the International Society for Pediatric and Adolescent Diabetes, all 3 organizations being represented by members who participated in the writing process.
Seizures in 204 comatose children: incidence and outcome
TLDR
Electroencephalographic monitoring allows the detection of subtle CS and NCS and is a prognostic tool in survivors of comatose children, and are associated with an unfavourable outcome in survivors.
A randomized trial of hyperglycemic control in pediatric intensive care.
TLDR
This multicenter, randomized trial showed that tight glycemic control in critically ill children had no significant effect on major clinical outcomes, although the incidence of hypoglycemia was higher with tight glucose control than with conventional glucose control.
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children
TLDR
A large cohort of international experts was able to achieve consensus regarding many recommendations for the best care of children with sepsis, acknowledging that most aspects of care had relatively low quality of evidence resulting in the frequent issuance of weak recommendations.
Acute lung injury in children: Therapeutic practice and feasibility of international clinical trials*
TLDR
This study reveals inconsistent mechanical ventilation practice and use of adjunctive therapies in children with acute lung injury and estimates that a large number of centers are needed to conduct clinical trials and it is imperative to bring about international collaboration.
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