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- Publications
- Influence
Microtubule Minus-End Binding Protein CAMSAP2 Controls Axon Specification and Dendrite Development
- K. Yau, Sam F.B. van Beuningen, +15 authors C. Hoogenraad
- Biology, Medicine
- Neuron
- 4 June 2014
In neurons, most microtubules are not associated with a central microtubule-organizing center (MTOC), and therefore, both the minus and plus-ends of these non-centrosomal microtubules are found… Expand
New constraints on oscillation parameters from v(e) appearance and v(mu) disappearance in the NOvA experiment
- M. A. Acero, P. Adamson, +126 authors R. Zwaska
- Physics
- 31 May 2018
For full abstract please refer to Official URL link”, or if there is a document attached which contains the abstract, “For full abstract please refer to attached document
MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis*
- Qingyang Liu, F. Liu, +7 authors A. Akhmanova
- Biology, Medicine
- The Journal of Biological Chemistry
- 15 August 2016
During cytokinesis, the antiparallel array of microtubules forming the central spindle organizes the midbody, a structure that anchors the ingressed cleavage furrow and guides the assembly of… Expand
Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport
- R. Tas, Anaël Chazeau, B. M. Cloin, Maaike L. A. Lambers, C. Hoogenraad, L. Kapitein
- Chemistry, Medicine
- Neuron
- 20 December 2017
Summary Microtubules are essential for polarized transport in neurons, but how their organization guides motor proteins to axons or dendrites is unclear. Because different motors recognize distinct… Expand
A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large
- S. Waaijers, J. Muñoz, +16 authors M. Boxem
- Biology, Medicine
- BMC Biology
- 9 August 2016
BackgroundAffinity purification followed by mass spectrometry (AP/MS) is a widely used approach to identify protein interactions and complexes. In multicellular organisms, the accurate identification… Expand
Myosin-V Induces Cargo Immobilization and Clustering at the Axon Initial Segment
- Anne F J Janssen, R. Tas, Petra van Bergeijk, Rosalie Oost, C. Hoogenraad, L. Kapitein
- Biology, Medicine
- Front. Cell. Neurosci.
- 28 August 2017
The selective transport of different cargoes into axons and dendrites underlies the polarized organization of the neuron. Although it has become clear that the combined activity of different motors… Expand
TRIM46 Organizes Microtubule Fasciculation in the Axon Initial Segment
- M. Harterink, K. Vocking, +12 authors C. Hoogenraad
- Biology, Medicine
- The Journal of Neuroscience
- 9 April 2019
Selective cargo transport into axons and dendrites over the microtubule network is essential for neuron polarization. The axon initial segment (AIS) separates the axon from the somatodendritic… Expand
Three-Step Model for Polarized Sorting of KIF17 into Dendrites
- M. Franker, M. R. Silva, +7 authors C. Hoogenraad
- Biology, Medicine
- Current Biology
- 11 July 2016
Kinesin and dynein motors drive bidirectional cargo transport along microtubules and have a critical role in polarized cargo trafficking in neurons [1, 2]. The kinesin-2 family protein KIF17 is a… Expand
Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry
- P. Schätzle, M. R. Silva, R. Tas, E. Katrukha, C. Hoogenraad
- Biology, Medicine
- Current Biology
- 9 July 2018
In neurons, microtubules form dense bundles and run along the length of axons and dendrites. Occasionally, dendritic microtubules can grow from the shaft directly into dendritic spines. Microtubules… Expand
Feedback-Driven Assembly of the Axon Initial Segment
- Amélie Fréal, Dipti Rai, +13 authors C. Hoogenraad
- Chemistry, Medicine
- Neuron
- 23 October 2019
Summary The axon initial segment (AIS) is a unique neuronal compartment that plays a crucial role in the generation of action potential and neuronal polarity. The assembly of the AIS requires… Expand