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Quantitation of feline leukaemia virus viral and proviral loads by TaqMan real-time polymerase chain reaction.
Feline leukaemia virus (FeLV) infection in cats is not only of veterinary importance but also a well-acknowledged animal model for studying the pathogenesis of retroviral disease. After virusExpand
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HERV-K-specific T cells eliminate diverse HIV-1/2 and SIV primary isolates.
The genetic diversity of HIV-1 represents a major challenge in vaccine development. In this study, we establish a rationale for eliminating HIV-1-infected cells by targeting cellular immune responsesExpand
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Vaccination against the feline leukaemia virus: outcome and response categories and long-term follow-up.
Feline leukaemia virus (FeLV) is a pathogen inducing fatal disease in cats worldwide. By applying sensitive molecular assays, efficacious commonly used FeLV vaccines that protect cats fromExpand
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Detection of Feline Leukemia Virus RNA in Saliva from Naturally Infected Cats and Correlation of PCR Results with Those of Current Diagnostic Methods
ABSTRACT A novel diagnostic test for feline leukemia virus (FeLV) RNA in saliva from naturally infected cats is described in this study. We evaluated different diagnostic tests and compared them withExpand
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Fecal shedding of infectious feline leukemia virus and its nucleic acids: a transmission potential.
Although it is assumed that fecal shedding of feline leukemia virus (FeLV) constitutes a transmission potential, no study has been performed showing that feces of infected cats can be a source ofExpand
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Reassessment of feline leukaemia virus (FeLV) vaccines with novel sensitive molecular assays.
We previously described antigen negative, provirus positive cats. Subsequently, we hypothesized that efficacious FeLV vaccines cannot prevent minimal viral replication. Thus, we vaccinated cats withExpand
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How molecular methods change our views of FeLV infection and vaccination.
FeLV was discovered 40 years ago and vaccines have been commercially available for almost two decades. So far, most FeLV pathogenesis and vaccine studies were conducted assaying parameters, such asExpand
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Shedding of feline leukemia virus RNA in saliva is a consistent feature in viremic cats.
The purpose of this investigation was to characterize the shedding pattern of feline leukemia virus (FeLV) RNA in saliva, and to correlate it with the proviral load in whole blood, viral load inExpand
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Copy number polymorphism of endogenous feline leukemia virus-like sequences.
In the cat genome, endogenous feline leukemia virus (enFeLV) exists as multiple, nearly full-length proviral sequences. Even though no infectious virus is produced from enFeLV sequences,Expand
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Association between endogenous feline leukemia virus loads and exogenous feline leukemia virus infection in domestic cats.
Recently, we demonstrated that endogenous feline leukemia virus (enFeLV) loads may vary among cats of different populations and that FeLV-infected cats have higher enFeLV loads than uninfected cats.Expand
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