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Successful Gastric Submucosal Tumor Resection Using Laparoscopic and Endoscopic Cooperative Surgery
BackgroundLaparoscopic wedge resections are increasingly utilized to treat gastric submucosal tumors (SMTs). However, laparoscopic wedge resection is not applicable for tumors located near theExpand
Neutralization of IL-10 Restores the Downregulation of IL-18 Receptor on Natural Killer Cells and Interferon-&ggr; Production in Septic Mice, Thus Leading to an Improved Survival
ABSTRACT The objective of the study was to investigate the mechanisms of insufficient interferon-&ggr; (IFN-&ggr;) response to interleukin 18 (IL-18) and the treatment for the insufficient responseExpand
Systemic inflammatory response syndrome as a predictor of anastomotic leakage after esophagectomy
PurposeEsophageal anastomotic leakage is still a major cause of morbidity and mortality after esophagectomy. We conducted this study to elucidate how anastomotic leakage affects the systemicExpand
Individualized surgery for early gastric cancer guided by sentinel node biopsy.
BACKGROUND We have reported that lymphatic mapping using indocyanine green (ICG) solution can be a good tool for identifying sentinel nodes (SNs) in gastric cancer. The purpose of this study was toExpand
Computed tomography lymphography for the detection of sentinel nodes in patients with gastric carcinoma
The sentinel node (SN) concept has been found to be feasible in gastric cancer. However, the lymphatic network of gastric cancer may be more complex, and it may be difficult to visualize all the SNExpand
Postoperative serum concentrations of high mobility group box chromosomal protein-1 correlates to the duration of SIRS and pulmonary dysfunction following gastrointestinal surgery.
OBJECTIVE To clarify the time course of changes in the serum HMGB-1 concentrations in patients undergoing major gastrointestinal surgery, and to investigate whether the serum HMGB-1 levels correlateExpand
Video-assisted thoracoscopic surgery for esophageal cancer attenuates postoperative systemic responses and pulmonary complications.
BACKGROUND Less invasive operations such as laparoscopic surgery have been developed for treating gastrointestinal malignancies. However, the advantages of video-assisted thoracoscopic surgery forExpand
CD47 is an adverse prognostic factor and a therapeutic target in gastric cancer
CD47 is an antiphagocytic molecule that acts via ligation to signal regulatory protein alpha on phagocytes; its enhanced expression and therapeutic targeting have recently been reported for severalExpand
Removal of increased circulating CD4+CD25+Foxp3+ regulatory T cells in patients with septic shock using hemoperfusion with polymyxin B-immobilized fibers.
BACKGROUND Although sepsis-induced immunosuppression has long been considered to be a factor in the late mortality of patients with sepsis, little is known about regulatory T cell (Treg)-mediatedExpand
Effects of Neutrophil Elastase Inhibitor on Progression of Acute Lung Injury Following Esophagectomy
The purpose of this study was to evaluate the effect of sivelestat sodium hydrate, a selective inhibitor of neutrophil elastase in the systemic inflammatory response, pulmonary function, and theExpand