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CF-1 minimal inbred mice were given technical DDT mixed into the diet at the dose levels of 2, 10, 50 and 250 parts per million (ppm) for the entire life span for two consecutive generations.… Continue Reading
The storage levels of DDT and its metabolites, following the long term administration of technical DDT at the dose levels of 2, 20, 50 and 250 ppm to mice, were evaluated in the fat tissue, liver,… Continue Reading
Benign osteomas occurring in CF-1 mice late in life were observed through 6 consecutive generations, their average incidence being higher in control females (11·5%) than in control males (8·5%) and… Continue Reading
Groups of CF-1 mice were given 250 ppm of DDT mixed into the diet for 15 weeks or 30 weeks and killed at different time intervals. Following 30 weeks of treatment a similar proportion of male mice… Continue Reading
Many workers have induced carcinoma of the uterine cervix by apphcation of carcinogenic compounds, thus Teutschldnder (1926) induced carcinomata of the cervix in rats by application of coal tar.… Continue Reading