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Up‐Regulation of Connexin45 in Heart Failure
Introduction: Heart failure is associated with reduced expression of the major gap junction protein connexin43 (Cx43), which may contribute to arrhythmias and sudden cardiac death in this patientExpand
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Ischemia Induces Closure of Gap Junctional Channels and Opening of Hemichannels in Heart-derived Cells and Tissue
Aim: Gap junction intercellular communication (GJIC) and hemichannel permeability may have important roles during an ischemic insult. Our aim was to evaluate the effect of ischemia on gap junctionExpand
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Overexpression of cardiac connexin45 increases susceptibility to ventricular tachyarrhythmias in vivo.
Electrophysiological remodeling involving gap junctions has been demonstrated in failing hearts and may contribute to intercellular uncoupling, delayed conduction, enhanced arrhythmias, andExpand
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PET-CT in the sub-arctic region of Norway 2010–2013. At the edge of what is possible?
TLDR
We analysed retrospectively all data on the PET-CT exams performed at the Section of Nuclear Medicine, Department of Radiology during a 32 months time period 2010–13. Expand
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Injury coding in a national trauma registry: a one-year validation audit in a level 1 trauma centre
BackgroundHospitals must improve patient safety and quality continuously. Clinical quality registries can drive such improvement. Trauma registries code injuries according to the Abbreviated InjuryExpand
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Heptanol triggers cardioprotection via mitochondrial mechanisms and mitochondrial potassium channel opening in rat hearts
Aim:  To investigate mechanisms behind heptanol (Hp)‐induced infarct size reduction and in particular if protection by pre‐treatment with Hp is triggered through mitochondrial mechanisms.
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Repeated Simulated Ischemia and Protection Against Gap Junctional Uncoupling
Ischemic preconditioning increases the heart's tolerance to a subsequent longer ischemic period. The aim of this study was to investigate the effect of early and delayed preconditioning on gapExpand
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An acylation‐Finkelstein approach to radioiodination of bioactives: The role of amide group anchimeric assistance
Herein, we report a straightforward sequential acylation-Finkelstein approach to achieve iodination of amine containing bioactives. The utility was demonstrated by successful radiolabelling with 123IExpand
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Copper-Mediated Late-Stage Iodination and 123I-Labelling of Triazole-benzimidazole Bioactives
The copper-mediated azide-alkyne cycloaddition has been studied to achieve late-stage introduction of iodine onto novel triazole-benzimidazole Gonadotropin Releasing Hormone (GnRH)-receptorExpand
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Quantitative PET/MR imaging of lung cancer in the presence of artifacts in the MR-based attenuation correction maps
Background Positron emission tomography (PET)/magnetic resonance (MR) imaging may become increasingly important for assessing tumor therapy response. A prerequisite for quantitative PET/MR imaging isExpand
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