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Major Histocompatibility Complex Class I–restricted Cross-presentation Is Biased towards High Dose Antigens and Those Released during Cellular Destruction
Naive T cells recirculate mainly within the secondary lymphoid compartment, but once activated they can enter peripheral tissues and perform effector functions. To activate naive T cells, foreignExpand
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Clinical Significance of Diffusely Increased 18F-FDG Uptake in the Thyroid Gland
Our purpose was to determine the clinical significance of diffusely increased 18F-FDG uptake in the thyroid gland as an incidental finding on PET/CT. Methods: All patients who were found to haveExpand
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18F-FDG Metabolic Tumor Volume and Total Glycolytic Activity of Oral Cavity and Oropharyngeal Squamous Cell Cancer: Adding Value to Clinical Staging
18F-FDG metabolic tumor volume (MTV) and total glycolytic activity (TGA) have been proposed as potential prognostic imaging markers for patient outcome in human solid tumors. The purpose of thisExpand
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Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing.
BACKGROUND To determine genomic alterations in head and neck squamous cell carcinoma (HNSCC) using formalin-fixed, paraffin-embedded (FFPE) tumors obtained through routine clinical practice, selectedExpand
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Value of PET/CT in the management of primary hepatobiliary tumors, part 2.
OBJECTIVE Primary hepatobiliary malignancies consist of hepatocellular carcinoma, cholangiocarcinoma, and gallbladder cancer. Benign hepatic lesions include hepatic cysts, hemagiomas, adenomas, andExpand
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Brain PET in the Diagnosis of Alzheimer’s Disease
Objectives The aim of this article was to review the current role of brain PET in the diagnosis of Alzheimer dementia. The characteristic patterns of glucose metabolism on brain FDG-PET can help inExpand
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FDG-PET/CT imaging biomarkers in head and neck squamous cell carcinoma.
This article discusses the value of 18F-fluoro-2-deoxyglucose PET/CT imaging biomarkers in head and neck squamous cell carcinoma. 18F-fluoro-2-deoxyglucose PET/CT is valuable at baseline staging,Expand
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FDG PET metabolic tumor volume segmentation and pathologic volume of primary human solid tumors.
OBJECTIVE The purpose of this study was to establish the correlation and reliability among the pathologic tumor volume and gradient and fixed threshold segmentations of (18)F-FDG PET metabolic tumorExpand
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Head and Neck PET/CT: Therapy Response Interpretation Criteria (Hopkins Criteria)—Interreader Reliability, Accuracy, and Survival Outcomes
There has been no established qualitative system of interpretation for therapy response assessment using PET/CT for head and neck cancers. The objective of this study was to validate the HopkinsExpand
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