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Schizosaccharomyces pombe Mti2 and Mti3 act in conjunction during mitochondrial translation initiation
TLDR
The characterization of the fission yeast Schizosaccharomyces pombe mtIF2 and mtIF3 suggests that Mti2 and Mti3 bind in a sequential manner to the small subunit of the mitoribosome and that Mounti3 facilitates the function of Mti 2 in mitochondrial translation initiation. Expand
The fission yeast Schizosaccharomyces pombe Mtf2 is required for mitochondrial cox1 gene expression.
TLDR
The results suggest that unlike its counterpart in S. cerevisiae which plays a general role in synthesis of mtDNA-encoded proteins, S. pombe Mtf2 primarily functions in cox1 translation and the effect of mtf2 deletion on splicing of introns in mtDNA is likely due to a deficiency in the synthesis of intron-encoding maturases. Expand