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Prognostic factors for surgical treatment of soft-tissue sarcomas in dogs: 75 cases (1986-1996).
TLDR
On the basis of a low local recurrence rate and high median survival time, wide excision of tumor margins or radical surgery appeared to be an effective means for managing soft-tissue sarcomas of the trunk and extremities. Expand
Multilobular osteochondrosarcoma in 39 dogs: 1979-1993.
TLDR
Older, large-breed dogs with multilobular osteochondrosarcoma each presented primarily with a fixed mass involving the flat bones of the skull, and Histological grade, surgical margins, and tumor location affected outcome. Expand
Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics.
TLDR
It is discovered that minicells can be packaged with therapeutically significant concentrations of chemotherapeutics of differing charge, hydrophobicity, and solubility, which is a factor critical for limiting systemic toxicity that should allow the use of complex regimens of combination chemotherapy. Expand
Multilobular osteochondrosarcoma of the canine skull: 16 cases (1978-1988).
TLDR
Excision with histologically complete surgical margins appeared to offer good opportunity for long-term tumor control in dogs with multilobular osteochondrosarcoma, and the role of adjuvant chemotherapy and radiotherapy in the management of MLO remains unclear. Expand
Comparative aspects of osteosarcoma. Dog versus man.
TLDR
Canine osteosarcoma is a readily available and highly comparable spontaneously occurring cancer that should be useful in a better understanding of the same disease in humans. Expand
Limb-sparing treatment for osteosarcoma in dogs.
TLDR
Multimodality limb-sparing treatment is believed to be a viable alternative for appropriately selected dogs with osteosarcoma and generally associated with better function than were limb- Sparing procedures performed on hind limbs. Expand
Use of single-agent carboplatin as adjuvant or neoadjuvant therapy in conjunction with amputation for appendicular osteosarcoma in dogs.
TLDR
Carboplatin treatment improves the survival probability in dogs with appendicular OSA compared to amputation alone and remains an acceptable alternative to adjuvant treatment with cisplatin. Expand
Improved Survival Associated With Postoperative Wound Infection in Dogs Treated With Limb-Salvage Surgery for Osteosarcoma
TLDR
In dogs with osteosarcoma treated with limb-salvage surgery, infection has a positive influence on survival, as does a smaller initial length of radius involved and lower body weight. Expand
Biodegradable Cisplatin Polymer in Limb-Sparing Surgery for Canine Osteosarcoma
TLDR
Local tumor recurrence may be decreased after limb-sparing surgery by use of biodegradable implants impregnated with chemotherapeutic agents, according to univariate analyses. Expand
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