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Dose-response study of N,N-dimethyltryptamine in humans. II. Subjective effects and preliminary results of a new rating scale.
- R. Strassman, C. Qualls, E. Uhlenhuth, R. Kellner
- Medicine, PsychologyArchives of General Psychiatry
- 1 February 1994
Clinical and preliminary quantitative data provide bases for further psychopharmacologic characterization of DMT's properties in humans and may be used to compare the effects of other agents affecting relevant brain receptors in volunteer and psychiatric populations.
Human Psychopharmacology of Hoasca, A Plant Hallucinogen Used in Ritual Context in Brazil
Assessment of 15 long-term members of a syncretic church that utilizes hoasca as a legal, psychoactive sacrament as well as 15 matched controls with no prior history of hoasca ingestion revealed high functional status.
Psilocybin-assisted treatment for alcohol dependence: A proof-of-concept study
- M. Bogenschutz, A. Forcehimes, J. Pommy, C. Wilcox, P. Barbosa, R. Strassman
- Psychology, MedicineJournal of Psychopharmacology
- 13 January 2015
A single-group proof-of-concept study to quantify acute effects of psilocybin in alcohol-dependent participants and to provide preliminary outcome and safety data, providing a strong rationale for controlled trials with larger samples to investigate efficacy and mechanisms.
Dose-response study of N,N-dimethyltryptamine in humans. I. Neuroendocrine, autonomic, and cardiovascular effects.
Dimethyltryptamine can be administered safely to experienced hallucinogen users and dose-response data generated for several measures hypothesized under serotonergic modulatory control may prove useful in psychopharmacological investigations of drug-induced and endogenous alterations in brain function.
DMT: The Spirit Molecule: A Doctor's Revolutionary Research into the Biology of Near-Death and Mystical Experiences
- R. Strassman
- Biology, Mathematics
- 1 December 2000
Psychedelic Effects of Ketamine in Healthy Volunteers: Relationship to Steady‐state Plasma Concentrations
- A. Bowdle, A. Radant, D. Cowley, E. Kharasch, R. Strassman, P. Roy-Byrne
- Medicine, PsychologyAnesthesiology
- 1 January 1998
Subanesthetic doses of ketamine produce psychedelic effects in healthy volunteers and the relation between steady‐state venous plasma ketamine concentrations and effects is highly linear between 50 and 200 ng/ml.
Human psychopharmacology of N,N-dimethyltryptamine
- R. Strassman
- Psychology, BiologyBehavioural Brain Research
- 15 December 1995
Ketamine psychotherapy for heroin addiction: immediate effects and two-year follow-up.
Differential tolerance to biological and subjective effects of four closely spaced doses of N,N-dimethyltryptamine in humans
ADVERSE REACTIONS TO PSYCHEDELIC DRUGS. A REVIEW OF THE LITERATURE
- R. Strassman
- Psychology, MedicineJournal of Nervous and Mental Disease
- 1 October 1984
The basic pharmacology of the major synthetic psychedelic compounds (primarily lysergic acid diethylamide [LSD]-25) is described and reference is made to their potentially beneficial psychological effects.