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Age dependence of primary motor cortex plasticity induced by paired associative stimulation
TLDR
A LTP-like plasticity dependence on age was found in female only, suggesting caution in interpreting behavioural studies on learning abilities in dependence onAge, and a reduction of the PAS-induced M1 plasticity in females after menopause was documented. Expand
Dietary and lifestyle guidelines for the prevention of Alzheimer's disease
TLDR
At the International Conference on Nutrition and the Brain, Washington, DC, July 19-20, 2013, speakers were asked to comment on possible guidelines for Alzheimer's disease prevention, with an aim of developing a set of practical, albeit preliminary, steps to be recommended to members of the public. Expand
d‐penicillamine reduces serum oxidative stress in Alzheimer’s disease patients
TLDR
A pilot study is presented examining the efficacy of the copper‐chelating agent d‐penicillamine in reducing oxidative stress in AD patients and its role in sustaining oxidative mechanisms in Alzheimer's disease. Expand
GSTO1*E155del polymorphism associated with increased risk for late-onset Alzheimer's disease: Association hypothesis for an uncommon genetic variant
TLDR
It is hypothesized that GSTO1*E155del is an uncommon genetic variant associated with AD risk and may be implicated in the modulation of arsenic neurotoxicity. Expand
Excess of nonceruloplasmin serum copper in AD correlates with MMSE, CSF β-amyloid, and h-tau
TLDR
The authors' results confirm the existence of changes in copper component distribution, particularly the copper fraction unexplained by ceruloplasmin and support the hypothesis of a β-amyloid and copper connection in Alzheimer disease. Expand
Longitudinal prognostic value of serum “free” copper in patients with Alzheimer disease
TLDR
Results show an association between copper deregulation and unfavorable evolution of cognitive function in Alzheimer disease, and further research is needed to establish whether copper is an independent risk factor for cognitive decline. Expand
Apolipoprotein E and alpha brain rhythms in mild cognitive impairment: A multicentric Electroencephalogram study
TLDR
The present multicentric EEG study tested the hypothesis that presence of ε4 affects sources of resting EEG rhythms in both MCI and AD subjects. Expand
Promoter haplotypes of interleukin-10 gene and sporadic Alzheimer's disease
TLDR
The results provide new insights on a possible involvement of the IL-10 gene in susceptibility to sporadic AD even though further functional and genetic investigations are necessary to clarify its role in AD. Expand
Implications of metal exposure and liver function in Parkinsonian patients resident in the vicinities of ferroalloy plants
TLDR
The results suggest the possibility that, in this area, a lifetime exposure to neurotoxicants and to Mn in particular, when accompanied to a subclinical liver dysfunction, may pose an increased risk for neurodegenerative disorders via metal metabolism abnormalities. Expand
Elevation of serum copper levels in Alzheimer’s disease
TLDR
Copper may play a role in neurodegenerative processes in AD, and serum copper measurement may prove to be a peripheral diagnostic marker for AD. Expand
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