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The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission 1
Purpose: Focal cortical dysplasias (FCD) are localized regions of malformed cerebral cortex and are very frequently associated with epilepsy in both children and adults. A broad spectrum of… Expand
Terminology and classification of the cortical dysplasias
Background: There have been difficulties in achieving a uniform terminology in the literature regarding issues of classification with respect to focal cortical dysplasias (FCDs) associated with… Expand
Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: a European consensus statement.
This work proposes formal diagnostic criteria and a therapeutic pathway for the management of RE patients, and summarizes recent data on the pathogenesis, clinical and paraclinical presentation, and therapeutic approaches. Expand
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
Several monoclonal antibodies that target the S glycoprotein of SARS-CoV-2, which was identified from memory B cells of an individual who was infected with severe acute respiratory syndrome coronavirus (SARS- coV) in 2003, and one antibody (named S309) potently neutralization, which may limit the emergence of neutralization-escape mutants. Expand
Focal cortical dysplasia: neuropathological subtypes, EEG, neuroimaging and surgical outcome.
A simplified classification of focal cortical dysplasias based on easily recognized histopathological characteristics and avoids complicated terminology is proposed, while the distinctive ensemble of other characteristics defines clinically homogeneous groups. Expand
GABAergic Neurons in Mammalian Thalamus: A Marker of Thalamic Complexity?
- P. Arcelli, C. Frassoni, M. Regondi, S. Biasi, R. Spreafico
- Medicine, Biology
- Brain Research Bulletin
- 31 December 1997
Thalamic GABAergic local circuit neurons are not directly related to the ability to perform specific sensorimotor tasks, but they are likely to reflect an increasing complexity of the local information processing that occurs at thalamic level. Expand
Intrinsic properties of nucleus reticularis thalami neurones of the rat studied in vitro.
- G. Avanzini, M. de Curtis, F. Panzica, R. Spreafico
- Chemistry, Medicine
- The Journal of physiology
- 1 September 1989
The presence of strong after‐hyperpolarizing potentials (SAHP and BAHP) in RTN neurones plays a significant role in determining two different functional states, defined as tonic and oscillatory burst firing modes, respectively. Expand
International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: A Task Force report from the ILAE Commission on Diagnostic Methods
The proposed international consensus classification of hippocampal neuronal cell loss will aid in the characterization of specific clinicopathologic syndromes, and explore variability in imaging and electrophysiology findings, and in postsurgical seizure control. Expand
Focal cortical dysplasias: MR imaging, histopathologic, and clinical correlations in surgically treated patients with epilepsy.
- N. Colombo, L. Tassi, +4 authors R. Spreafico
- AJNR. American journal of neuroradiology
- 1 April 2003
In patients with FCD, Taylor's F CD and non-Taylor's FCD can usually be distinguished with MR imaging, although some overlap exists. Expand
In situ labeling of apoptotic cell death in the cerebral cortex and thalamus of rats during development
- R. Spreafico, C. Frassoni, P. Arcelli, M. Selvaggio, S. de Biasi
- Biology, Medicine
- The Journal of comparative neurology
- 11 December 1995
Differences in the number of apoptotic cells between cortex and thalamus suggest that apoptotic cell death may have a different functional significance in the two brain areas. Expand