• Publications
  • Influence
The exogenous origin of trimethylamine in the mouse.
Although it is now generally regarded that the origin of urinary trimethylamine (TMA) is via the action of intestinal microflora on precursors such as choline, little direct evidence exists. TheExpand
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Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor.
To acquire transforming potential, the precursor of the Ras oncoprotein must undergo farnesylation of the cysteine residue located in a carboxyl-terminal tetrapeptide. Inhibitors of the enzyme thatExpand
  • 569
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Quantitation of glycosaminoglycan hexosamine using 3-methyl-2-benzothiazolone hydrazone hydrochloride.
Abstract This procedure allows analysis of hexosamine present in glycosaminoglycans under conditions of mild acid treatment. It utilizes the color complex formed by interaction ofExpand
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Lowry determination of protein in the presence of Triton X-100.
Abstract The Lowry procedure has been modified for use in the presence of Triton X-100 (TX-100) by the addition of 10% sodium dodecyl sulfate. The method is applicable to samples containing 40–120 μgExpand
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Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors.
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Relationship between MRI relaxation time and muscle fiber composition.
The relationship between nuclear magnetic resonance relaxation time obtained with magnetic resonance imaging (MRI) and muscle fiber composition of the lateral gastrocnemius was examined in 13 men.Expand
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Trimethylaminuria associated with seizures and behavioural disturbance: A case report
A 16-year-old left-handed male is presented with a history of seizures associated with a fish-like odour and behavioural disturbances thought to be related to trimethylaminuria. His seizures wereExpand
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A study of the vanadate-trapped state of the (Na,K)-ATPase. Evidence against interacting nucleotide site models.
The state of the Na+- and K+-stimulated adenosine triphosphatase ((Na,K)-ATPase) which binds vanadate was investigated by taking advantage of the slow rate of vanadate release (koff = 0.32/h at 25Expand
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Titration of activated bovine Factor X.
  • R. Smith
  • Medicine, Biology
  • The Journal of biological chemistry
  • 10 April 1973
Abstract p-Nitrophenyl-p'-guanidinobenzoate is a suitable substrate for the titration of purified bovine Factor X which has been activated by a coagulant protein from Russell's viper venom. ReactionExpand
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