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Augmented increase in tight junction permeability by luminal stimuli in the non-inflamed ileum of Crohn's disease
Background: Crohn's disease is associated with deranged intestinal permeability in vivo, suggesting dysfunction of tight junctions. The luminal contents are important for development ofExpand
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Defunctioning Stoma Reduces Symptomatic Anastomotic Leakage After Low Anterior Resection of the Rectum for Cancer: A Randomized Multicenter Trial
Objective:The aim of this randomized multicenter trial was to assess the rate of symptomatic anastomotic leakage in patients operated on with low anterior resection for rectal cancer and who wereExpand
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Early predictors of glucocorticosteroid treatment failure in severe and moderately severe attacks of ulcerative colitis
Objective To analyse the ability of simple clinical and biochemical parameters to predict glucocorticosteroid (GCS) treatment failure in patients with acute attacks of ulcerative colitis.Expand
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Randomized comparison of straight and colonic J pouch anastomosis after low anterior resection.
OBJECTIVE The authors compared clinical bowel function and complications of a low anterior resection with either a straight or colonic J pouch anastomosis. SUMMARY BACKGROUND DATA Urgency andExpand
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Surgical approaches to obtaining optimal bowel function.
Approximately 50% of patients have an unsatisfactory functional result after traditional restorative rectal resection, and an even higher percentage, at least in the early postoperative period,Expand
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Natural course of Crohn's disease after ileocolic resection: endoscopically visualised ileal ulcers preceding symptoms.
Forty two Crohn's disease patients were followed up after ileocolic resection with regard to symptoms and endoscopic appearance of the ileocolic anastomosis. Twenty eight patients resected because ofExpand
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The Swedish rectal cancer registry
An audit of all patients with rectal cancer in Sweden was launched in 1995. This is the first report from the Swedish Rectal Cancer Registry (SRCR).
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What Is the Risk for a Permanent Stoma After Low Anterior Resection of the Rectum for Cancer? A Six-Year Follow-Up of a Multicenter Trial
PURPOSE: The aim of this study was to assess the risk for permanent stoma after low anterior resection of the rectum for cancer. METHODS: In a nationwide multicenter trial 234 patients undergoing lowExpand
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Occurrence and prognostic importance of micrometastases in regional lymph nodes in Dukes' B colorectal carcinoma: an immunohistochemical study.
OBJECTIVE To evaluate the incidence and prognostic importance of micrometastatic disease in regional lymph nodes from Dukes' B colorectal carcinomas. DESIGN Retrospective study. SETTINGExpand
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Different intestinal permeability patterns in relatives and spouses of patients with Crohn’s disease: an inherited defect in mucosal defence?
Background A familial defect in intestinal barrier function has been found in Crohn’s disease. Aim To investigate possible genetic and environmental influences on this barrier defect by studyingExpand
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