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Nicotinic acid hydrazones: a novel anticonvulsant pharmacophore
A series of aryl acid hydrazones of substituted aromatic acid hydrazides (D1 to D20) were synthesised and evaluated for anticonvulsant activity. Aryl acid hydrazones of Nicotinic acid hydrazide (D8,Expand
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Menthone aryl acid hydrazones: a new class of anticonvulsants.
A series of ten compounds (Compounds J(1)-J(10)) of (±) 3-menthone aryl acid hydrazone was synthesized and characterized by thin layer chromatography and spectral analysis. Synthesized compounds wereExpand
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Study of Convolvulus pluricaulis for antioxidant and anticonvulsant activity.
Convolvulus pluricaulis Choisy is a perennial wild herb commonly found on sandy & rocky areas under xerophytic conditions in northern India. It is a reputed drug of ayurveda and reported to possesExpand
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Synthesis and screening of substituted thiosemicarbazone derivatives: an approach towards novel anticonvulsant search.
A series of thiosemicarbazones of halogen substituted benzaldehydes, benzophenone and acetophenone were synthesized using an appropriate synthetic route and characterized by thin layer chromatographyExpand
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HEPATOPROTECTIVE ACTIVITY OF ALCOHOLIC AND AQUEOUS EXCTRACTS OF WEDELIA CHINENSIS
Summary The hepatoprotective effect of alcoholic and aqueous extract of whole plant of Wedelia chinensis was monitored by estimating the serum transaminases (SGOT, SGPT), Serum alkaline phosphataseExpand
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A questionnaire survey of stigma related to human immunodeficiency virus infection/acquired immunodeficiency syndrome among healthy population
Background and Objectives: Human immunodeficiency virus (HIV)-related stigma is present at all levels which act as critical barriers for effectively addressing it. This also influences the treatmentExpand
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Menthone semicarbazides and thiosemicarbazides as anticonvulsant agents.
A series of novel (+/-) 3-menthone semi carbazides (1-7) and thiosemicarbazides synthesized using an appropriate synthetic route and characterized by thin layer chromatography and spectral analysis.Expand
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Synthesis and Evaluation of Schiff Bases for Anticonvulsant and Behavioral Depressant Properties
A series of Schiff bases of menthone has been synthesized using an appropriate synthetic route and characterized using Thin Layer Chromatography and spectral analysis. The synthesized compounds wereExpand
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In silico validation and structure activity relationship study of a series of pyridine-3-carbohydrazide derivatives as potential anticonvulsants in generalized and partial seizures.
A series of twelve compounds (Compounds RNH1-RNH12) of acid hydrazones of pyridine-3-carbohydrazide or nicotinic acid hydrazide was synthesized and evaluated for anticonvulsant activity by MES,Expand
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Synthesis and anticonvulsant activities of small n-substituted 2, 5-dimethyl pyrrole and bipyrrole
A series of N-substituted 2, 5-dimethyl pyrrole and bipyrrole derivatives were synthesized by Paal-Knorr method and evaluated for anticonvulsant activity at NIH. Anticonvulsant activity wasExpand
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