• Publications
  • Influence
Distribution of androgen and estrogen receptor mRNA‐containing cells in the rat brain: An in situ hybridization study
TLDR
AR and ER may modulate nonolfactory sensory information as well since labeled cells were found in regions involved in the central relay of somatosensory information, including the mesencephalic nucleus of the trigeminal nerve, the ventral thalamic nuclear group, and the dorsal horn of the spinal cord.
Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.
TLDR
The high degree of conservation, distinct pharmacology, and unique neuronal distribution of the MC4 receptor suggest specific and complex roles for the melanocortin peptides in neuroendocrine and autonomic control.
Trophic Action of Leptin on Hypothalamic Neurons That Regulate Feeding
TLDR
The results suggest that leptin plays a neurotrophic role during the development of the hypothalamus and that this activity is restricted to a neonatal critical period that precedes leptin's acute regulation of food intake in adults.
Organization of projections from the medial nucleus of the amygdala: A PHAL study in the rat
TLDR
Functional evidence suggests that circuits associated with dorsal regions of the ventral division may deal with reproductive behavior, whereas circuitsassociated with ventral regions ofThe ventral Division may deal preferentially with agonistic behavior.
Organization of projections from the ventromedial nucleus of the hypothalamus: A Phaseolus vulgaris‐Leucoagglutinin study in the rat
The organization of projections from the four parts of the ventromedial nucleus (VMH) and a ventrolaterally adjacent region tentatively identified as the tuberal nucleus (TU) have been analyzed with
Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain.
  • R. Simerly
  • Biology, Psychology
    Annual review of neuroscience
  • 2002
TLDR
This review focuses on the organization of interconnected limbic-hypothalamic pathways that participate in the neural control of reproduction and summarizes what is known about the developmental neurobiology of these pathways.
Formation of Projection Pathways from the Arcuate Nucleus of the Hypothalamus to Hypothalamic Regions Implicated in the Neural Control of Feeding Behavior in Mice
TLDR
New insight is provided into development of hypothalamic circuits and an anatomical basis for the delayed postnatal regulation of food intake and body weight by leptin is suggested.
Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system.
TLDR
The location and properties of this receptor provide a pharmacological basis for the action of POMC peptides produced in the brain and possibly a specific physiological role for gamma-MSH.
Connections of the posterior nucleus of the amygdala
TLDR
Experiments with fluorogold and phaseolus vulgaris leucoagglutinin (PHAL) indicate that the major neuronal input to the PA arises in the ventral premammillary nucleus, and that substantial projections also arise in olfactory‐related areas such as the medial nucleus of the amygdala.
Early Life Programming and Neurodevelopmental Disorders
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