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A drug burden index to define the functional burden of medications in older people.
TLDR
The drug burden index demonstrates that anticholinergic and sedative drug exposure is associated with poorer function in community-dwelling older people and provides a useful evidence-based tool for assessing the functional effect of exposure to medications in this population. Expand
The metabolic syndrome, inflammation, and risk of cognitive decline.
TLDR
Findings support the hypothesis that the metabolic syndrome contributes to cognitive impairment in elders, but primarily in those with high level of inflammation. Expand
Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years: A Randomized Clinical Trial.
TLDR
Among ambulatory adults aged 75 years or older, treating to an SBP target of less than 120 mm Hg compared with an SBp target of more than 140mm Hg resulted in significantly lower rates of fatal and nonfatal major cardiovascular events and death from any cause. Expand
Falls Among Adult Patients Hospitalized in the United States: Prevalence and Trends
TLDR
In this large sample of hospitals, fall and injurious fall prevalence varied by nursing unit type in U.S. hospitals, with a small, but statistically significant, decrease in falls over the 27-month study. Expand
Diabetes-related complications, glycemic control, and falls in older adults
TLDR
In older diabetic adults, reducing diabetes-related complications may prevent falls, and achieving lower A1C levels with oral hypoglycemic medications was not associated with more frequent falls, but, among those using insulin, A 1C ≤6% increased fall risk. Expand
Gait Speed Predicts Decline in Attention and Psychomotor Speed in Older Adults: The Health Aging and Body Composition Study
TLDR
In this cohort of older community dwellers, gait speed independently predicted a decline in Digit Symbol Substitution Test after 5 years. Expand
Financial difficulty in acquiring food among elderly disabled women: results from the Women's Health and Aging Study.
TLDR
Financial difficulty acquiring food was common, and receipt of nutritional services was rare, in community-dwelling, older disabled women, and nutrition assistance programs for the elderly should reexamine their effectiveness in preventing nutritional deficits in olderdisabled women. Expand
Is it possible to identify risks for injurious falls in hospitalized patients?
TLDR
Few variables were able to distinguish patients who sustained injury after a hospital fall, further challenging clinicians' efforts to minimize hospital-related fall injury. Expand
Changes in antipsychotic drug use in nursing homes during implementation of the OBRA-87 regulations.
TLDR
A substantial decrease in antipsychotic drug use coincided with the implementation of OBRA-87, which is consistent with an improvement in quality of nursing home care, and further research is needed to determine the effects of this legislation on resident outcomes. Expand
Diabetes, Hyperglycemia, and Inflammation in Older Individuals
TLDR
The findings show that dysglycemia is associated with inflammation, and this relationship, although consistent in diabetic individuals, also extends to those with IFG/IGT. Expand
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