• Publications
  • Influence
Self-assembling Peptide Scaffolds Promote Enamel Remineralization
TLDR
The results suggest that self-assembling peptides may be useful in the modulation of mineral behavior during in situ dental tissue engineering. Expand
The chemistry of enamel caries.
TLDR
For the future, delivering fluoride deep into the lesion would appear to offer the prospect of improved repair, and elucidation of the role of organic material may also reveal putative mechanisms for encouraging repair and/or protecting the enamel mineral. Expand
Architecture of Intact Natural Human Plaque Biofilms Studied by Confocal Laser Scanning Microscopy
TLDR
An in situ device for the in vivo generation of intact dental plaque biofilms on natural tooth surfaces in human subjects showed a more open architecture, consistent with recent models of biofilm structure from other habitats and has important implications for the delivery of therapeutics to desired targets within the plaque. Expand
Mutations in CNNM4 Cause Jalili Syndrome, Consisting of Autosomal-Recessive Cone-Rod Dystrophy and Amelogenesis Imperfecta
TLDR
The identification of CNNM4 as the causative gene for Jalili syndrome, characterized by syndromic CRD with AI, has the potential to provide new insights into the roles of metal transport in visual function and biomineralization. Expand
Penetration of Fluoride into Natural Plaque Biofilms
TLDR
Penetration of fluoride into plaque biofilms during brief topical exposure is restricted, which may limit anti-caries efficacy, and fluoride penetration increased with duration of NaF exposure. Expand
The chemistry of enamel development.
TLDR
Towards the end of secretion, matrix is replaced by fluid followed by massive crystal growth during maturation, probably as a result of comprehensive destruction of molecules which might impair crystal growth. Expand
The developing enamel matrix: nature and function.
TLDR
The aim of this review was to survey the current knowledge of enamel matrix proteins with a view to suggesting possible functions of these proteins, which could lead to incomplete maturation of the enamel and the eruption of dysplastic tissue. Expand
The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice
TLDR
Results show that integrity of the SI–ameloblast interface is essential for normal enamel mineralization and shows that nectin-1 may also participate in the regulation of desmosome assembly. Expand
Nephrocalcinosis (Enamel Renal Syndrome) Caused by Autosomal Recessive FAM20A Mutations
TLDR
This au-tosomal recessive disorder, also known as enamel renal syndrome, of FAM20A causes nephrocalcinosis and amelogenesis imperfecta and it is speculated that all individuals with biallelic FAM 20A mutations will eventually show neph reciprocalcinosis. Expand
Effect of surface zone deproteinisation on the access of mineral ions into subsurface carious lesions of human enamel.
TLDR
Results indicated that uptake was improved by removal of organic material, and the role of organic (proteinaceous) material in restricting the movement of mineral ions into carious lesions in vitro. Expand
...
1
2
3
4
5
...