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Effects of Glucagon-Like Peptide-1 in Patients With Acute Myocardial Infarction and Left Ventricular Dysfunction After Successful Reperfusion
Background—Glucose-insulin-potassium infusions are beneficial in uncomplicated patients with acute myocardial infarction (AMI) but are of unproven efficacy in AMI with left ventricular (LV)… Expand
Diabetic cardiomyopathy: the search for a unifying hypothesis.
Although diabetes is recognized as a potent and prevalent risk factor for ischemic heart disease, less is known as to whether diabetes causes an altered cardiac phenotype independent of coronary… Expand
Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure.
- George Sokos, L. Nikolaidis, S. Mankad, D. Elahi, R. Shannon
- Journal of cardiac failure
- 1 December 2006
BACKGROUND Insulin resistance is present in the setting of congestive heart failure. Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin with both insulinotropic and insulinomimetic… Expand
Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node-positive, human…
- E. Tan-chiu, G. Yothers, +13 authors J. Bryant
- Journal of clinical oncology : official journal…
- 1 November 2005
PURPOSE Trastuzumab is effective in treating human epidermal growth factor receptor 2 (HER2) -positive breast cancer, but it increases frequency of cardiac dysfunction (CD) when used with or after… Expand
Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy.
- L. Nikolaidis, D. Elahi, You-tang Shen, R. Shannon
- American journal of physiology. Heart and…
- 1 December 2005
We have shown previously that the glucagon-like peptide-1 (GLP-1)-(7-36) amide increases myocardial glucose uptake and improves left ventricular (LV) and systemic hemodynamics in both conscious dogs… Expand
Direct Effects of Glucagon-Like Peptide-1 on Myocardial Contractility and Glucose Uptake in Normal and Postischemic Isolated Rat Hearts
- T. Zhao, P. Parikh, +4 authors R. Shannon
- Chemistry, Medicine
- Journal of Pharmacology and Experimental…
- 1 June 2006
Recent evidence suggests that glucagon-like peptide-1 (GLP-1) enhances recovery of left ventricular (LV) function after transient coronary artery occlusion. However, it is uncertain whether GLP-1 has… Expand
Recombinant Glucagon-Like Peptide-1 Increases Myocardial Glucose Uptake and Improves Left Ventricular Performance in Conscious Dogs With Pacing-Induced Dilated Cardiomyopathy
Background—The failing heart demonstrates a preference for glucose as its metabolic substrate. Whether enhancing myocardial glucose uptake favorably influences left ventricular (LV) contractile… Expand
Understanding why patients of low socioeconomic status prefer hospitals over ambulatory care.
- S. Kangovi, F. Barg, T. Carter, J. Long, R. Shannon, D. Grande
- Psychology, Medicine
- Health affairs
- 1 July 2013
Patients with low socioeconomic status (SES) use more acute hospital care and less primary care than patients with high socioeconomic status. This low-value pattern of care use is harmful to these… Expand
Effect of glucagon-like peptide-1 (GLP-1) on glycemic control and left ventricular function in patients undergoing coronary artery bypass grafting.
- George Sokos, H. Bolukoglu, +9 authors R. Shannon
- The American journal of cardiology
- 1 September 2007
Increasing evidence suggests that tight glycemic control improves clinical outcomes after coronary artery bypass grafting (CABG). However, the risk for hypoglycemia with insulin often results in less… Expand
HIV-1 Nef is associated with complex pulmonary vascular lesions in SHIV-nef-infected macaques.
- J. Marecki, C. Cool, +9 authors S. C. Flores
- American journal of respiratory and critical care…
- 15 August 2006
RATIONALE HIV-infected patients with pulmonary arterial hypertension have histologic manifestations that are indistinguishable from those found in patients with idiopathic pulmonary arterial… Expand