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Finger protein of novel structure encoded by hunchback, a second member of the gap class of Drosophila segmentation genes
The DNA sequence of hunchback, a Drosophila segmentation gene of the gap class, reveals that like Krüppel, the first gap gene analysed, it encodes a protein with finger motifs typical of a class ofExpand
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The claudin-like megatrachea is essential in septate junctions for the epithelial barrier function in Drosophila.
Vertebrate claudin proteins are integral components of tight junctions, which function as paracellular diffusion barriers in epithelia. We identified Megatrachea (Mega), a Drosophila transmembraneExpand
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spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo.
The region specific homeotic gene spalt (sal) of Drosophila melanogaster promotes the specification of terminal pattern elements as opposed to segments in the trunk. Our results show that theExpand
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A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene
Krüppel (Kr), a segmentation gene of Drosophila, encodes a protein sharing structural features of the DNA-binding "finger motif" of TFIIIA, a Xenopus transcription factor. Low-stringencyExpand
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A conserved activation element in BMP signaling during Drosophila development
The transforming growth factor β (TGF-β) family member Decapentaplegic (Dpp) is a key regulator of patterning and growth in Drosophila development. Previous studies have identified a short DNA motifExpand
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Xenopus Xsal-1, a vertebrate homolog of the region specific homeotic gene spalt of Drosophila
We have isolated an amphibian homolog of the homeotic gene spalt of Drosophila. Like its Drosophila counterpart the Xenopus Xsal-1 gene encodes a protein that contains three widely separated sets ofExpand
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The tracheae defective gene encodes a bZIP protein that controls tracheal cell movement during Drosophila embryogenesis
The tracheae defective (tdf) gene is required for the formation of the tracheal system during Drosophila embryogenesis. It encodes a putative bZIP transcription factor (TDF). Antibodies directedExpand
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Cross-regulatory interactions among the gap genes of Drosophila
Segmentation of the Drosophila embryo involves expression of several classes of zygotic genes in response to positional information of maternal origin1. Zygotic expression of the gap genes is thoughtExpand
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Analysis of Krüppel protein distribution during early Drosophila development reveals posttranscriptional regulation
We have examined the spatial and temporal patterns of expression of the Krüppel (Kr) protein, a gap gene product, during Drosophila embryogenesis. Antibodies directed against the Kr protein revealedExpand
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Wurst is essential for airway clearance and respiratory-tube size control
The Drosophila melanogaster tracheal system and the mammalian lung are branching networks of tubular epithelia that convert during late embryogenesis from liquid- to air-filling. Little is knownExpand
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