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Toxicology and carcinogenic action of pyrrolizidine alkaloids.
Summary The studies of the hepatoxic and hepatocarcinogenic pyrrolizidine alkaloids (PA) have shown that ( a ) The conventional testing for toxicity and its evaluation on the basis of death occurringExpand
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Carcinogenic Activity of N-Methyl-N-nitroso-N′-nitroguanidine
N-METHYL-N-NITROSOURETHANE (MNU) (I) and its ethyl homologue have been found to be effective carcinogens, which can induce stomach, oesophageal, intestinal and lung tumours with one or a fewExpand
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Pathological Changes in Rats as a Result of Treatment with Monocrotaline
ImagesFigs. 6-9Figs. 2-5Figs. 10-12
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Senecio Alkaloids: Primary Liver Tumours in Rats as a Result of Treatment with (1) A Mixture of Alkaloids from S. Jacobaea Lin.; (2) Retrorsine; (3) Isatidine*
ImagesFigs. 5-10Figs. 11-13Figs. 14-17Figs. 1-4
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Aflatoxins and ‘Albinism’ in Plants
obtained. Above ). 680 mμ fewer quanta are required per mole acetic acid assimilated, on an average 8·3. Several times figures as low as 7·5 and 6·8 wore registered at A 716 and 723 mμ. Table 2Expand
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Cardiovascular lesions and various tumors found in rats given T-2 toxin, a trichothecene metabolite of Fusarium.
White rats given intragastrically 3alpha-hydroxy-4beta,15-diacetoxy-8alpha-(3-methylbutyryloxy)-12,13-epoxy-tricholthec-9-en (T-2 toxin), a trichothecene metabolite of several Fusarium species,Expand
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