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Improved imaging of liver metastases with stimulated acoustic emission in the late phase of enhancement with the US contrast agent SH U 508A: early experience.
PURPOSE To see whether stimulated acoustic emission (SAE) in the liver parenchyma in the late phase of enhancement with SH U 508A increases the conspicuity of occult metastases at ultrasonography… Expand
Contrast‐Enhanced Transcranial Color‐Coded Real‐time Sonography: Results of a Phase‐Two Study
Background and Purpose Transcranial color-coded real-time sonography has been developed as a promising new bedside procedure to monitor central nervous system parenchymal and vascular pathology; the… Expand
Stimulated Acoustic Emission: Nonbackscatter Contrast Effect of Microbubbles Seen with Harmonic Power Doppler Imaging
Transient imaging has been introduced to enhance the signal intensities when using echo contrast agents. However, this phenomenon is not clearly understood. To evaluate the mechanisms of this… Expand
Quantitative echo contrast concentration measurement by Doppler sonography.
The hypothesis investigated in this study is that Doppler ultrasound can be used to make quantitative echo contrast concentration measurements in flow systems. Our motivation was to demonstrate the… Expand
A mathematical model for the assessment of hemodynamic parameters using quantitative contrast echocardiography
- Xucai Chen, K. Schwarz, D. Phillips, S. Steinmetz, R. Schlief
- IEEE Transactions on Biomedical Engineering
- 1 June 1998
A mathematical model for the assessment of hemodynamic parameters using quantitative echocardiography is presented. Expand
Stimulated acoustic emission to image a late liver and spleen-specific phase of Levovist in normal volunteers and patients with and without liver disease.
- M. Blomley, T. Albrecht, +7 authors R. Schlief
- Ultrasound in medicine & biology
- 1 November 1999
Quantitative studies were performed to investigate liver- specific uptake of the microbubble Levovist, using stimulated acoustic emission (SAE), which can detect microbubbles even when stationary or… Expand
Color Doppler ultrasound of liver lesions: Signal enhancement after intravenous injection of the ultrasound contrast agent Levovist®
- H. Ernst, E. G. Hahn, T. Balzer, R. Schlief, N. Heyder
- Journal of clinical ultrasound : JCU
- 1 January 1996
Patients with focal liver lesions (hemangioma, focal nodular hyperplasia, adenoma, hepatocellular carcinoma, metastatic lesions, focal fatty lesion) received the ultrasound contrast agent Levovist®… Expand
An investigation of the relationship between ultrasound echo enhancement and Doppler frequency shift using a pulsatile arterial flow phantom.
RATIONALE AND OBJECTIVES Based on the echo-enhancing effect of microbubbles, various agents have been developed to improve the diagnostic confidence in patients with inadequate Doppler signals. In… Expand
Basic properties and results of clinical trials of ultrasound contrast agents based on galactose.
- R. Schlief, R. Schurman, H. Niendorf
- Annals of the Academy of Medicine, Singapore
- 1 September 1993
The development of reproducible echogenic contrast agents, which contain physiologically degradable acoustic strays in micrometre dimensions, has been under way for several years; all currently known… Expand
Volumetric arterial flow quantification using echo contrast. An in vitro comparison of three ultrasonic intensity methods: radio frequency, video and Doppler.
- K. Schwarz, G. Bezante, X. Chen, J. G. Mottley, R. Schlief
- Materials Science, Medicine
- Ultrasound in medicine & biology
The two hypotheses presented in this paper are: (1) absolute and relative volumetric flow rates in vessels can be measured by echo contrast time-intensity curves; and (2) echo contrast time-intensity… Expand